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nectin-3 抗体 (AA 92-296)

This anti-nectin-3 antibody is a 兔 多克隆 antibody detecting nectin-3 in WB, ELISA, IHC 和 FACS. Suitable for 人.
产品编号 ABIN7602666
发货至: 中国

Quick Overview for nectin-3 抗体 (AA 92-296) (ABIN7602666)

抗原

See all nectin-3 (NECTIN3) 抗体
nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

适用

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宿主

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克隆类型

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多克隆

标记

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This nectin-3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
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    AA 92-296

    原理

    Anti-Nectin 3/NECTIN3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Nectin 3/NECTIN3 Antibody Picoband® (ABIN7602666). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Nectin 3/NECTIN3 recombinant protein (Position: E92-N296).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Inagaki, M., Irie, K., Ishizaki, H., Tanaka-Okamoto, M., Miyoshi, J., Takai, Y. Role of cell adhesion molecule nectin-3 in spermatid development. Genes Cells 11: 1125-1132, 2006. 2. Mizoguchi, A., Nakanishi, H., Kimura, K., Matsubara, K., Ozaki-Kuroda, K., Katata, T., Honda, T., Kiyohara, Y., Heo, K., Higashi, M., Tsutsumi, T., Sonoda, S., Ide, C., Takai, Y. Nectin: an adhesion molecule involved in formation of synapses. J. Cell Biol. 156: 555-565, 2002. 3. Reymond, N., Borg, J.-P., Lecocq, E., Adelaide, J., Campadelli-Fiume, G., Dubreuil, P., Lopez, M. Human nectin3/PRR3: a novel member of the PVR/PRR/nectin family that interacts with afadin. Gene 255: 347-355, 2000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

    别名

    NECTIN3

    背景

    Synonyms: Nectin-3, CDw113, Nectin cell adhesion molecule 3, Poliovirus receptor-related protein 3, CD113, NECTIN3, PRR3, PVRL3

    Tissue Specificity: Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines.

    Background: Nectin-3, also known as poliovirus receptor-related 3, is a 95 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. It is mapped to 3q13.13. This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of ional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.

    分子量

    80 kDa

    基因ID

    25945

    途径

    Cell-Cell Junction Organization
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