nectin-3 抗体 (Extracellular, N-Term)
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Quick Overview for nectin-3 抗体 (Extracellular, N-Term) (ABIN7043441)
抗原
See all nectin-3 (NECTIN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 84-97, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to Nectin-3/PVRL3
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Human,rat - identical
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产品特性
- Anti-Nectin-3/PVRL3 (extracellular) Antibody (ABIN7043441, ABIN7044696 and ABIN7044697) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot, live cell flow cytometry, and immunohistochemistry applications. It has been designed to recognize Nectin-3 from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)ETITQISWEKIHGK, corresponding to amino acid residues 84-97 of mouse Nectin-3
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亚型
- IgG
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anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) antibody
NECTIN3 适用: 人 WB, IP, ICC, FACS 宿主: 兔 Monoclonal BLR307M unconjugated Recombinant Antibody
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 282-404) antibodyNECTIN3 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6D5B2 unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 59-166) antibodyNECTIN3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 90-293) antibodyNECTIN3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 1-366) antibodyNECTIN3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (Internal Region) antibodyNECTIN3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 310-549) antibodyNECTIN3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 92-296) antibodyNECTIN3 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 171-377) antibodyNECTIN3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 1-366) antibodyNECTIN3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 2.5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:100
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7235987)
Blocking Peptide: (ABIN7235987)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
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别名
- NECTIN3
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背景
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Synonyms: Nectin cell adhesion molecule 3, Poliovirus receptor-related 3, CD113
Description: Nectins are Ca2+-independent immunoglobulin-like cell adhesion molecules that localize at adherens junctions between two neighboring cells. They play an important role in mediating asymmetric homotypic and heterotypic cell-cell adhesions. The nectin family contains four members, nectin-1-4, which are encoded by the PVRL1-4 genes, respectively. Nectin-3 is localized mostly in dendrites and partly in axons and is crucial for the specific interactions between axons and dendrites and proper formation of the synapse1,2. Its structure consists of an extracellular region with three immunoglobulin-like loops, one V type and two C2 types.Nectins binds afadin at its c-terminal region and connects to the actin cytoskeleton. This interaction plays a major role in the formation of various cell-cell junctions in cooperation with or independently of cadherins cell adhesion molecules1,2.Nectins also regulates numerous cellular functions, such as cell movement, proliferation, polarization, survival and differentiation by interacting with various proteins1.
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基因ID
- 58998
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NCBI登录号
- NM_015480
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UniProt
- Q9JLB9
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途径
- Cell-Cell Junction Organization
抗原
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