DBN1 抗体 (AA 9-649)
Quick Overview for DBN1 抗体 (AA 9-649) (ABIN7602638)
抗原
See all DBN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 9-649
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原理
- Anti-Drebrin/DBN1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Drebrin/DBN1 Antibody Picoband® (ABIN7602638). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Drebrin/DBN1 recombinant protein (Position: H9-D649).
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亚型
- IgG
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anti-Drebrin 1 (DBN1) (AA 150-281) antibody
DBN1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal DBN1-2879 unconjugated
anti-Drebrin 1 (DBN1) (AA 1-326) antibody (PE)DBN1 适用: 人 ICFC 宿主: 小鼠 Monoclonal DBN-N-03 PE
anti-Drebrin 1 (DBN1) (Internal Region) antibodyDBN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 1-649) antibodyDBN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-Drebrin 1 (DBN1) (AA 1-326) antibodyDBN1 适用: 人 WB, FACS, MS 宿主: 小鼠 Monoclonal DBN-N-03 unconjugated
anti-Drebrin 1 (DBN1) (AA 401-596) antibodyDBN1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 350-649) antibodyDBN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 3-134) antibodyDBN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 151-250) antibodyDBN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 194-228) antibodyDBN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB56246 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat, Monkey
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Akbar, M., Kim, H. Y. Protective effects of docosahexaenoic acid in staurosporine-induced apoptosis: involvement of phosphatidylinositol-3 kinase pathway. J. Neurochem. 82: 655-665, 2. Calon, F., Lim, G. P., Yang, F., Morihara, T., Teter, B., Ubeda, O., Rostaing, P., Triller, A., Salem, N., Jr., Ashe, K. H., Frautschy, S. A., Cole, G. M. Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model. Neuron 43: 633-645, 2004. 3. Harigaya, Y., Shoji, M., Shirao, T., Hirai, S. Disappearance of actin-binding protein, drebrin, from hippocampal synapses in Alzheimer's disease. J. Neurosci. Res. 43: 87-92, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- DBN1 (Drebrin 1 (DBN1))
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别名
- DBN1
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背景
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Synonyms: Spermine oxidase, Polyamine oxidase 1, PAO-1, PAOh1, Smox, Smo
Tissue Specificity: Widely expressed. Isoform 1 and isoform 2 are expressed at higher level in brain and skeletal muscle. Isoform 7 is found in brain and spleen, isoform 10 is widely expressed but found at lower level in heart, kidney, liver and lung.
Background: Drebrin is a protein that in humans is encoded by the DBN1 gene. The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
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分子量
- 120 kDa
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基因ID
- 1627
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UniProt
- Q16643
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途径
- Maintenance of Protein Location
抗原
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