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DVL2 抗体 (AA 89-576)

This anti-DVL2 antibody is a 兔 多克隆 antibody detecting DVL2 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602612
发货至: 中国

Quick Overview for DVL2 抗体 (AA 89-576) (ABIN7602612)

抗原

See all DVL2 抗体
DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

适用

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人, 小鼠, 大鼠

宿主

  • 68
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克隆类型

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多克隆

标记

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This DVL2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 89-576

    原理

    Anti-DVL2 Antibody Picoband®

    产品特性

    Anti-DVL2 Antibody Picoband® (ABIN7602612). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human DVL2 recombinant protein (Position: L89-Y576). Human DVL2 shares 97.3% amino acid (aa) sequence identity with mouse DVL2.
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Capelluto, D. G. S., Kutateladze, T. G., Habas, R., Finkielstein, C. V., He, X., Overduin, M. The DIX domain targets dishevelled to actin stress fibres and vesicular membranes. Nature 419: 726-729, 2002. 2. Chen, W., ten Berge, D., Brown, J., Ahn, S., Hu, L. A., Miller, W. E., Caron, M. G., Barak, L. S., Nusse, R., Lefkowitz, R. J. Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of frizzled 4. Science 301: 1391-1394, 2003. 3. Greco, T. L., Sussman, D. J., Camper, S. A. Dishevelled-2 maps to human chromosome 17 and distal to Wnt3a and vestigial tail (vt) on mouse chromosome 11. Mammalian Genome 7: 475-476, 1996.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

    别名

    DVL2

    背景

    Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.

    分子量

    85 kDa

    基因ID

    132299

    UniProt

    O14641

    途径

    Tube Formation
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