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TLR5 抗体 (AA 81-766)

This anti-TLR5 antibody is a 兔 多克隆 antibody detecting TLR5 in WB 和 ELISA. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7602531
发货至: 中国

Quick Overview for TLR5 抗体 (AA 81-766) (ABIN7602531)

抗原

See all TLR5 抗体
TLR5 (Toll-Like Receptor 5 (TLR5))

适用

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小鼠, 大鼠

宿主

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克隆类型

  • 91
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多克隆

标记

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This TLR5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 81-766

    原理

    Anti-Tlr5 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Tlr5 Antibody Picoband® (ABIN7602531). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Tlr5 recombinant protein (Position: Q81-D766).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Andersen-Nissen, E., Hawn, T. R., Smith, K. D., Nachman, A., Lampano, A. E., Uematsu, S., Akira, S., Aderem, A. Cutting edge: Tlr5-/- mice are more susceptible to Escherichia coli urinary tract infection. J. Immun. 178: 4717-4720, 2007. 2. Andersen-Nissen, E., Smith, K. D., Bonneau, R., Strong, R. K., Aderem, A. A conserved surface on Toll-like receptor 5 recognizes bacterial flagellin. J. Exp. Med. 204: 393-403, 2007. 3. Burdelya, L. G., Krivokrysenko, V. I., Tallant, T. C., Strom, E., Gleiberman, A. S., Gupta, D., Kurnasov, O. V., Fort, F. L., Osterman, A. L., DiDonato, J. A., Feinstein, E., Gudkov, A. V. An agonist of Toll-like receptor 5 has radioprotective activity in mouse and primate models. Science 320: 226-230, 2008.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    TLR5 (Toll-Like Receptor 5 (TLR5))

    别名

    Tlr5

    背景

    Synonyms: Beta-2-microglobulin, B2m

    Tissue Specificity: Detected in lung, spleen, uterus, vagina and epididymis. .

    Background: Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene. Predicted to enable interleukin-1 receptor binding activity and signaling receptor activity. Predicted to be involved in several processes, including positive regulation of interleukin-8 production, positive regulation of nitric oxide biosynthetic process, and positive regulation of toll-like receptor signaling pathway. Predicted to act upstream of or within innate immune response. Predicted to be located in membrane. Predicted to be integral component of plasma membrane. Is expressed in brain, olfactory epithelium, spinal cord, and trunk unsegmented mesenchyme. Human ortholog(s) of this gene implicated in Legionnaires' disease, cystic fibrosis, cystitis, melioidosis, and systemic lupus erythematosus. Orthologous to human TLR5 (toll like receptor 5).

    分子量

    100 kDa

    基因ID

    53791

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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