GLI1 抗体 (AA 800-1057)
Quick Overview for GLI1 抗体 (AA 800-1057) (ABIN7602517)
抗原
See all GLI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 800-1057
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原理
- Anti-GLI1 Antibody Picoband®
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产品特性
- Anti-GLI1 Antibody Picoband® (ABIN7602517). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GLI1 recombinant protein (Position: Y800-Q1057). Human GLI1 shares 79.8% amino acid (aa) sequence identity with mouse GLI1.
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anti-Zinc Finger Protein GLI1 (GLI1) (AA 601-700) antibody
GLI1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, FACS, IF (cc), IHC (p), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 284-449) antibodyGLI1 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1B9F8 unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (C-Term) antibodyGLI1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 805-820) antibodyGLI1 适用: 小鼠 WB, ELISA, IHC, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 401-500) antibodyGLI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 200-300) antibodyGLI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (C-Term) antibodyGLI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 805-820) antibodyGLI1 适用: 小鼠 WB, ELISA, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 921-1106) antibodyGLI1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 196-230) antibodyGLI1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB54395 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Kinzler KW, Bigner SH, Bigner DD, Trent JM, Law ML, O'Brien SJ, Wong AJ, Vogelstein B. (April 1987). "Identification of an amplified, highly expressed gene in a human glioma". Science 236 (4797): 70-3. 2. Ruiz i Altaba A. (June 1999). "Gli proteins encode context-dependent positive and negative functions: implications for development and disease.". Development 126 (14): 3205-16. 3. Sasaki H, Hui C, Nakafuku M, Kondoh H. (April 1997). "A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro". Development 124 (7): 1313-22. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GLI1 (Zinc Finger Protein GLI1 (GLI1))
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别名
- GLI1
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背景
- GLI1, also known as GLI, is a protein originally isolated in human glioblastoma. The protein is encoded by GLI1 gene. It is mapped to 12q13.3. This gene is a member of a select group of cellular genes that are genetically altered in primary human tumors. GLI1 encodes a member of the GLI-Kruppel family of zinc finger proteins in the final steps of Hedgehog signaling in normal development and disease. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Beside, various upstream patterning signals may be integrated by the Gli proteins to a coherent programme of neurogenesis.
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分子量
- 150 kDa
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基因ID
- 2735
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UniProt
- P08151
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途径
- Hedgehog Signaling, Dopaminergic Neurogenesis
抗原
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