Renin 抗体 (AA 80-370)
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北京 101111
Quick Overview for Renin 抗体 (AA 80-370) (ABIN7602514)
抗原
See all Renin (REN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-370
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原理
- Anti-Renin/REN Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Renin/REN Antibody (ABIN7602514). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Renin/REN recombinant protein (Position: N80-D370).
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亚型
- IgG
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anti-Renin (REN) (AA 67-153) antibody
REN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Renin (REN) (AA 24-406) antibodyREN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H2 unconjugated
anti-Renin (REN) (AA 331-406) antibodyREN 适用: 大鼠, 小鼠, 犬 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Renin (REN) (AA 67-153) antibodyREN 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Renin (REN) (AA 275-389) antibodyREN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 3# unconjugated
anti-Renin (REN) (AA 24-160) antibodyREN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Renin (REN) (AA 229-398) antibodyREN 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Renin (REN) (AA 65-264) antibodyREN 适用: 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Renin (REN) antibodyREN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB1615 unconjugated Recombinant Antibody
anti-Renin (REN) antibodyREN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Renin (REN)
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别名
- REN
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背景
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Synonyms: p-selectin glycoprotein ligand, Selplg, Psgl1
Tissue Specificity: Highly expressed in blood, bone marrow, brain, adipose tissue, spleen, and thymus. Also expressed in heart, kidney, liver, muscle, ovary, and stomach.
Background: This gene encodes renin, an aspartic protease that is secreted by the kidneys. Renin is a part of the renin-angiotensin-aldosterone system involved in regulation of blood pressure, and electrolyte balance. This enzyme catalyzes the first step in the activation pathway of angiotensinogen by cleaving angiotensinogen to form angiotensin I, which is then converted to angiotensin II by angiotensin I converting enzyme. This cascade can result in aldosterone release, narrowing of blood vessels, and increase in blood pressure as angiotension II is a vasoconstrictive peptide. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause hyperuricemic nephropathy familial juvenile 2, familial hyperproreninemia, and renal tubular dysgenesis.
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分子量
- 55 kDa
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基因ID
- 5972
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UniProt
- P00797
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
抗原
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