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Renin 抗体 (AA 80-370)

This anti-Renin antibody is a 兔多克隆 antibody detecting Renin in WB, IHC 和 ELISA. Suitable for 人, 大鼠和小鼠.

产品编号 ABIN7602514

发货至: 中国

Quick Overview for Renin 抗体 (AA 80-370) (ABIN7602514)

抗原

See all Renin (REN) 抗体

Renin (REN)

适用

72
57
38
19
3
2
1
1
1
1

人, 大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

82
18
12
6
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This Renin antibody is un-conjugated

应用范围

114
68
51
38
36
13
13
11
8
5
5
5
3
3
2
1
1

Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Discover our top product REN Primary Antibody

抗原表位
15

8

8

7

6

5

5

4

4

4

4

3

3

3

2

1

1

1

1

1

1

1

1

1
AA 80-370

原理

Anti-Renin/REN Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Renin/REN Antibody Picoband® (ABIN7602514). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Renin/REN recombinant protein (Position: N80-D370).

亚型

IgG
anti-Renin (REN) (AA 67-153) antibody
REN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Renin (REN) (AA 24-406) antibody
REN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H2 unconjugated

anti-Renin (REN) (Internal Region) antibody
REN 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Renin (REN) (AA 331-406) antibody
REN 适用: 大鼠, 小鼠, 犬 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Renin (REN) (AA 67-153) antibody
REN 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D2 unconjugated

anti-Renin (REN) (AA 275-389) antibody
REN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 3# unconjugated

anti-Renin (REN) (AA 65-264) antibody
REN 适用: 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Renin (REN) (AA 229-398) antibody
REN 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Renin (REN) antibody
REN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Renin (REN) (AA 24-406) antibody
REN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B5 unconjugated

应用备注

Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Abel, K. J., Gross, K. W. Close physical linkage of the murine Ren-1 and Ren-2 loci. Nucleic Acids Res. 16: 2111-2126, 1988. 2. Caron, K. M. I., James, L. R., Kim, H.-S., Knowles, J., Uhlir, R., Mao, L., Hagaman, J. R., Cascio, W., Rockman, H., Smithies, O. Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene. Proc. Nat. Acad. Sci. 101: 3106-3111, 2004. 3. Chirgwin, J. M., Schaefer, I. M., Diaz, J. A., Lalley, P. A. Mouse kidney renin gene is on chromosome one. Somat. Cell Molec. Genet. 10: 633-637, 1984.

限制

仅限研究用
状态

Lyophilized

溶解方式

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原

Renin (REN)

别名

REN

背景

Synonyms: p-selectin glycoprotein ligand, Selplg, Psgl1
Tissue Specificity: Highly expressed in blood, bone marrow, brain, adipose tissue, spleen, and thymus. Also expressed in heart, kidney, liver, muscle, ovary, and stomach.
Background: This gene encodes renin, an aspartic protease that is secreted by the kidneys. Renin is a part of the renin-angiotensin-aldosterone system involved in regulation of blood pressure, and electrolyte balance. This enzyme catalyzes the first step in the activation pathway of angiotensinogen by cleaving angiotensinogen to form angiotensin I, which is then converted to angiotensin II by angiotensin I converting enzyme. This cascade can result in aldosterone release, narrowing of blood vessels, and increase in blood pressure as angiotension II is a vasoconstrictive peptide. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause hyperuricemic nephropathy familial juvenile 2, familial hyperproreninemia, and renal tubular dysgenesis.

分子量

55 kDa

基因ID

5972

UniProt

P00797

途径

ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour

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