COPE 抗体 (AA 80-308) (DyLight 488)
Quick Overview for COPE 抗体 (AA 80-308) (DyLight 488) (ABIN7602510)
抗原
See all COPE 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 80-308
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原理
- Anti-Human COPE DyLight® 488 conjugated Antibody(monoclonal, 9B6)
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Human COPE DyLight® 488 conjugated Antibody (monoclonal, 9B6) (ABIN7602509)-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human COPE recombinant protein (Position: E80-A308). Human COPE shares 89.5% amino acid (aa) sequence identity with mouse COPE.
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亚型
- IgG2a
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应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: COPE coatomer protein complex, subunit epsilon". 2. Shima DT, Scales SJ, Kreis TE, Pepperkok R (November 1999). "Segregation of COPI-rich and anterograde-cargo-rich domains in endoplasmic-reticulum-to-Golgi transport complexes". Curr. Biol. 9 (15): 821-4.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- Lot specific
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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- COPE (Coatomer Protein Complex, Subunit epsilon (COPE))
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别名
- COPE
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背景
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Synonyms: Coatomer subunit epsilon, Epsilon-coat protein, Epsilon-COP, COPE
Tissue Specificity: Golgi apparatus membrane, Peripheral membrane protein, Cytoplasmic side, Cytoplasm, COPI-coated vesicle membrane, Peripheral membrane protein, Cytoplasmic side,
Background: Coatomer subunit epsilon is a protein that in humans is encoded by the COPE gene. The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
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分子量
- 39 kDa
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基因ID
- 11316
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UniProt
- O14579
抗原
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