SAV1 抗体 (AA 8-320)
Quick Overview for SAV1 抗体 (AA 8-320) (ABIN7602478)
抗原
See all SAV1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-320
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原理
- Anti-SAV1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SAV1 Antibody Picoband® (ABIN7602478). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SAV1 recombinant protein (Position: K8-H320).
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亚型
- IgG
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anti-Salvador Homolog 1 (SAV1) (AA 300-383) antibody
SAV1 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-Salvador Homolog 1 (SAV1) (AA 1-210) antibodySAV1 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Salvador Homolog 1 (SAV1) (AA 1-210) antibodySAV1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Salvador Homolog 1 (SAV1) antibodySAV1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Salvador Homolog 1 (SAV1) antibodySAV1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Salvador Homolog 1 (SAV1) (AA 1-383) antibodySAV1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Salvador Homolog 1 (SAV1) (AA 300-383) antibodySAV1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Salvador Homolog 1 (SAV1) (AA 65-92) antibodySAV1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Salvador Homolog 1 (SAV1) (AA 266-315) antibodySAV1 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Salvador Homolog 1 (SAV1) (AA 1-383) antibodySAV1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Heallen, T., Zhang, M., Wang, J., Bonilla-Claudio, M., Klysik, E., Johnson, R. L., Martin, J. F. Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size. Science 332: 458-461, 2011. 2. Leach, J. P., Heallen, T., Zhang, M., Rahmani, M., Morikawa, Y., Hill, M. C., Segura, A., Willerson, J. T., Martin, J. F. Hippo pathway deficiency reverses systolic heart failure after infarction. Nature 550: 260-264, 2017. 3. Tapon, N., Harvey, K. F., Bell, D. W., Wahrer, D. C. R., Schiripo, T. A., Haber, D. A., Hariharan, I. K. salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 110: 467-478, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SAV1 (Salvador Homolog 1 (SAV1))
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别名
- SAV1
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背景
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Synonyms: NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4, Mtnd4, mt-Nd4, Nd4
Tissue Specificity: Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney.
Background: Protein salvador homolog 1 is a protein that in humans is encoded by the SAV1 gene. WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
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分子量
- 45 kDa
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基因ID
- 60485
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UniProt
- Q9H4B6
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途径
- Stem Cell Maintenance
抗原
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