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CD1b 抗体 (AA 78-110)

This anti-CD1b antibody is a 兔 多克隆 antibody detecting CD1b in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602446
发货至: 中国

Quick Overview for CD1b 抗体 (AA 78-110) (ABIN7602446)

抗原

See all CD1b (CD1B) 抗体
CD1b (CD1B)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CD1b antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 78-110

    原理

    Anti-CD1B Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-CD1B Antibody Picoband® (ABIN7602446). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CD1B recombinant protein (Position: D78-Y110).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Beckman, E. M., Porcelli, S. A., Morita, C. T., Behar, S. M., Furlong, S. T., Brenner, M. B. Recognition of a lipid antigen by CD1-restricted alpha-beta(+) T cells. Nature 372: 691-694, 1994. 2. Park, S.-H., Bendelac, A. CD1-restricted T-cell responses and microbial infection. Nature 406: 788-792, 2000. 3. Sieling, P. A., Chatterjee, D., Porcelli, S. A., Prigozy, T. I., Mazzaccaro, R. J., Soriano, T., Bloom, B. R., Brenner, M. B., Kronenberg, M., Brennan, P. J., Modlin, R. L. CD1-restricted T cell recognition of microbial lipoglycan antigens. Science 269: 227-230, 1995.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    CD1b (CD1B)

    别名

    CD1B

    背景

    Synonyms: T-cell surface glycoprotein CD1b, CD1b, CD1B

    Tissue Specificity: Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

    Background: CD1B is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

    分子量

    40 kDa

    基因ID

    910

    UniProt

    P29016
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