电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CD1b 抗体

CD1B 适用: 人 FACS, IP, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal SN13 unconjugated
产品编号 ABIN1981866
发货至: 中国
  • 抗原 See all CD1b (CD1B) 抗体
    CD1b (CD1B)
    适用
    • 59
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 34
    • 26
    小鼠
    克隆类型
    • 35
    • 25
    单克隆
    标记
    • 29
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD1b antibody is un-conjugated
    应用范围
    • 27
    • 24
    • 21
    • 14
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The mouse monoclonal antibody SN13 (also known as K5-1B8) recognizes an extracellular epitope of CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    A cell membrane antigen preparation that was isolated from normal human thymocytes
    克隆位点
    SN13
    亚型
    IgG1 kappa
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze. Do not use after expiration date stamped on vial label.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Giuliani, Prete, Graziani, Aquino, Balduzzi, Sugita, Brenner, Iona, Fattorini, Orefici, Porcelli, Bonmassar: "Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells." in: Infection and immunity, Vol. 69, Issue 12, pp. 7461-70, (2001) (PubMed).

    Hayes, Knight: "Group 1 CD1 genes in rabbit." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 1, pp. 403-10, (2001) (PubMed).

    Tentori, Graziani, Porcelli, Sugita, Brenner, Madaio, Bonmassar, Giuliani, Aquino: "Rifampin increases cytokine-induced expression of the CD1b molecule in human peripheral blood monocytes." in: Antimicrobial agents and chemotherapy, Vol. 42, Issue 3, pp. 550-4, (1998) (PubMed).

  • 抗原
    CD1b (CD1B)
    别名
    CD1b (CD1B 产品)
    别名
    CD1 antibody, CD1A antibody, R1 antibody, CD1B3 antibody, CD1B antibody, CD1-b antibody, CD1b molecule antibody, T-cell surface glycoprotein CD1b-3 antibody, CD1b1 molecule antibody, T-cell surface glycoprotein CD1b1 antibody, CD1B antibody, LOC443423 antibody, CD1B1 antibody, LOC100720602 antibody
    背景
    CD1b molecule,CD1b (also known as R1) together with CD1a and c, belongs to group 1 of CD1 antigens. These non-classical MHC-like glycoproteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. The trafficking routes of the particular CD1 types differ and correspond to their ability to bind and present different groups of antigens. Besides non-peptide glycolipid antigen presentation to CD1-restricted T cells, CD1b has been implicated in thymocyte development.,R1
    基因ID
    910
    UniProt
    P29016
You are here:
客服