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Fibrillarin 抗体 (AA 77-138)

This 兔 多克隆 anti-Fibrillarin antibody specifically detects Fibrillarin in WB, IF, ELISA, ICC 和 FACS. The antibody is reactive with 人 和 猴 samples.
产品编号 ABIN7602434
发货至: 中国
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中国
北京 101111
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Room 801-803
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Quick Overview for Fibrillarin 抗体 (AA 77-138) (ABIN7602434)

抗原

See all Fibrillarin (FBL) 抗体
Fibrillarin (FBL)

适用

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人, 猴

宿主

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克隆类型

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多克隆

标记

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This Fibrillarin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
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    AA 77-138

    原理

    Anti-Fibrillarin/FBL Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Fibrillarin/FBL Antibody (ABIN7602434). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Monkey. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Fibrillarin/FBL recombinant protein (Position: K77-N138).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Monkey
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    Fibrillarin (FBL)

    别名

    FBL

    背景

    Synonyms: IFNGR2 protein, Interferon gamma receptor 2, IFNGR2, mCG_11456

    Tissue Specificity: Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.

    Background: rRNA 2'-O-methyltransferase fibrillarin is an enzyme that in humans is encoded by the FBL gene. This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.

    分子量

    37 kDa

    基因ID

    2091

    UniProt

    P22087

    途径

    Ribonucleoside Biosynthetic Process
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