SYCP3 抗体 (AA 75-236)
Quick Overview for SYCP3 抗体 (AA 75-236) (ABIN7602415)
抗原
See all SYCP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-236
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原理
- Anti-SCP3/SYCP3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-SCP3/SYCP3 Antibody Picoband® (ABIN7602415). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SCP3/SYCP3 recombinant protein (Position: E75-F236).
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亚型
- IgG
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anti-Synaptonemal Complex Protein 3 (SYCP3) (AA 27-128) antibody
SYCP3 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 6F9B6 unconjugated
anti-Synaptonemal Complex Protein 3 (SYCP3) (N-Term) antibodySYCP3 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 3 (SYCP3) (AA 145-250) antibodySYCP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 3 (SYCP3) (AA 13-46), (N-Term) antibodySYCP3 适用: 人 WB 宿主: 兔 Polyclonal RB49743 unconjugated
anti-Synaptonemal Complex Protein 3 (SYCP3) (AA 1-236) antibodySYCP3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 3 (SYCP3) antibodySYCP3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 3 (SYCP3) (AA 18-223) antibodySYCP3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 3 (SYCP3) (N-Term) antibodySYCP3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 3 (SYCP3) (C-Term) antibodySYCP3 适用: 小鼠 IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Martinez-Garay I, Jablonka S, Sutajova M, Steuernagel P, Gal A, Kutsche K (Sep 2002). "A new gene family (FAM9) of low-copy repeats in Xp22.3 expressed exclusively in testis: implications for recombinations in this region".Genomics 80 (3): 259-67. 2. Mallon AM, Platzer M, Bate R, Gloeckner G, Botcherby MR, Nordsiek G, Strivens MA, Kioschis P, Dangel A, Cunningham D, Straw RN, Weston P, Gilbert M, Fernando S, Goodall K, Hunter G, Greystrong JS, Clarke D, Kimberley C, Goerdes M, Blechschmidt K, Rump A, Hinzmann B, Mundy CR, Miller W, Poustka A, Herman GE, Rhodes M, Denny P, Rosenthal A, Brown SD (Aug 2000). "Comparative genome sequence analysis of the Bpa/Str region in mouse and Man". Genome Res 10 (6): 758-75. 3. Miyamoto, T., Hasuike, S., Yogev, L., Maduro, M. R., Ishikawa, M., Westphal, H., Lamb, D. J. Azoospermia in patients heterozygous for a mutation in SYCP3. Lancet 362: 1714-1719, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))
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别名
- SYCP3
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背景
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Synonyms: N-alpha-acetyltransferase 15, NatA auxiliary subunit,Gastric cancer antigen Ga19,N-terminal acetyltransferase,NMDA receptor-regulated protein 1,Protein tubedown-1,Tbdn100,NAA15,GA19, NARG1, NATH, TBDN100,
Tissue Specificity: Expressed at high levels in testis and in ocular endothelial cells. Also found in brain (corpus callosum), heart, colon, bone marrow and at lower levels in most adult tissues, including thyroid, liver, pancreas, mammary and salivary glands, lung, ovary, urogenital system and upper gastrointestinal tract. Overexpressed in gastric cancer, in papillary thyroid carcinomas and in a Burkitt lymphoma cell line (Daudi). Specifically suppressed in abnormal proliferating blood vessels in eyes of patients with proliferative diabetic retinopathy. .
Background: SYCP3, also known as COR1 or SCP3, is a protein that in humans is encoded by the SYCP3 gene. It is mapped to 12q23.2. This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein by dominant-negative interference. SYCP3 is linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes.
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分子量
- 35 kDa
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基因ID
- 50511
抗原
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