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DKK1 抗体 (AA 73-272)

This 兔 多克隆 anti-DKK1 antibody specifically detects DKK1 in ELISA 和 IHC. The antibody is reactive with 大鼠 和 小鼠 samples.
产品编号 ABIN7602383
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for DKK1 抗体 (AA 73-272) (ABIN7602383)

抗原

See all DKK1 抗体
DKK1 (Dickkopf Homolog 1 (DKK1))

适用

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大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This DKK1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    AA 73-272

    原理

    Anti-Dkk1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Dkk1 Antibody (ABIN7602383). Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Dkk1 recombinant protein (Position: N73-H272).

    亚型

    IgG
  • 应用备注

    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    DKK1 (Dickkopf Homolog 1 (DKK1))

    别名

    Dkk1

    背景

    Synonyms: Dickkopf-related protein 1, Dickkopf-1, Dkk-1, hDkk-1, SK, DKK1, UNQ492/PRO1008

    Tissue Specificity: Placenta.

    Background: DKK1, Dickkopf-related protein 1, is a protein that in humans is encoded by the DKK1 gene. This gene encodes a protein that is a member of the dickkopf family. By genomic sequence analysis, determined that the DKK1 gene contains 4 exons. The DKK1 gene is mapped to 10q11.2 using FISH. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

    分子量

    38 kDa

    基因ID

    13380

    UniProt

    O54908

    途径

    WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
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