NUP98 抗体 (AA 728-1787)
Quick Overview for NUP98 抗体 (AA 728-1787) (ABIN7602379)
抗原
See all NUP98 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 728-1787
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原理
- Anti-NUP98 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-NUP98 Antibody Picoband® (ABIN7602379). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NUP98 recombinant protein (Position: H728-I1787). Human NUP98 shares 89.1% and 89% amino acid (aa) sequence identity with mouse and rat NUP98, respectively.
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亚型
- IgG
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anti-Nucleoporin 98kDa (NUP98) (AA 1-466) antibody
NUP98 适用: 人, 小鼠, 大鼠, Saccharomyces cerevisiae, Schizosaccharomyces pombe WB, ELISA, IF, ICC, DB 宿主: 大鼠 Monoclonal 2H10 unconjugated
anti-Nucleoporin 98kDa (NUP98) (GLFG Motif), (N-Term) antibodyNUP98 适用: 人, 小鼠, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena WB, IF 宿主: 小鼠 Monoclonal 21A10 unconjugated
anti-Nucleoporin 98kDa (NUP98) (FGxxN Motif), (N-Term) antibodyNUP98 适用: 人, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena WB, IF 宿主: 小鼠 Monoclonal 13C2 unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 965-1110) antibodyNUP98 适用: 人 WB, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) antibodyNUP98 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Monoclonal 2H4 unconjugated Recombinant Antibody
anti-Nucleoporin 98kDa (NUP98) (AA 621-920) antibodyNUP98 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) antibodyNUP98 适用: 人 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 1-606) antibodyNUP98 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) antibodyNUP98 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 1-110) antibodyNUP98 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Laurell, E., Beck, K., Krupina, K., Theerthagiri, G., Bodenmiller, B., Horvath, P., Aebersold, R., Antonin, W., Kutay, U. Phosphorylation of Nup98 by multiple kinases is crucial for NPC disassembly during mitotic entry. Cell 144: 539-550, 2011. 2. Nakamura, T., Largaespada, D. A., Lee, M. P., Johnson, L. A., Ohyashiki, K., Toyama, K., Chen, S. J., Willman, C. L., Chen, I.-M., Feinberg, A. P., Jenkins, N. A., Copeland, N. G., Shaughnessy, J. D., Jr. Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7,11)(p15,p15) in human myeloid leukaemia. Nature Genet. 12: 154-158, 1996. 3. von Kobbe, C., van Deursen, J. M. A., Rodrigues, J. P., Sitterlin, D., Bachi, A., Wu, X., Wilm, M., Carmo-Fonseca, M., Izaurralde, E. Vesicular stomatitis virus matrix protein inhibits host cell gene expression by targeting the nucleoporin Nup98. Molec. Cell 6: 1243-1252, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NUP98 (Nucleoporin 98kDa (NUP98))
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别名
- NUP98
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Nuclear pore complex protein Nup98-Nup96 is a protein that in humans is encoded by the NUP98 gene. This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. NUP98 is a peripheral nucleoporin located at both the cytoplasmic and nuclear sides of the central channel of the NPC. NUP98 phosphorylation is critical for NPC disassembly at the onset of mitosis. It also plays roles in gene expression, mitotic checkpoint, and pathogenesis. Ligand blot analysis suggested that NUP98 can function as a docking protein for cytosol-mediated docking of import substrates. In addition to that, NUP98 is a target of the vesicular stomatitis virus M protein-mediated inhibition of mRNA nuclear export.
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分子量
- 98,105 kDa
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基因ID
- 4928
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UniProt
- P52948
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途径
- Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
抗原
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