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CHD1 抗体 (AA 71-1250)

This anti-CHD1 antibody is a 兔 多克隆 antibody detecting CHD1 in WB, ELISA, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602361
发货至: 中国

Quick Overview for CHD1 抗体 (AA 71-1250) (ABIN7602361)

抗原

See all CHD1 抗体
CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CHD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 71-1250

    原理

    Anti-CHD1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-CHD1 Antibody Picoband® (ABIN7602361). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CHD1 recombinant protein (Position: E71-D1250).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Delmas, V., Stokes, D. G., Perry, R. P. A mammalian DNA-binding protein that contains a chromodomain and an SNF2/SWI2-like helicase domain. Proc. Nat. Acad. Sci. 90: 2414-2418, 1993. 2. Flanagan, J. F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K. L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S. Double chromodomains cooperate to recognize the methylated histone H3 tail. Nature 438: 1181-1185, 2005. 3. Gaspar-Maia, A., Alajem, A., Polesso, F., Sridharan, R., Mason, M. J., Heidersbach, A., Ramalho-Santos, J., McManus, M. T., Plath, K., Meshorer, E., Ramalho-Santos, M. Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature 460: 863-868, 2009.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

    别名

    CHD1

    背景

    Synonyms: Hepatocyte growth factor-regulated tyrosine kinase substrate, Hrs, Protein pp110, HGS, HRS

    Tissue Specificity: Ubiquitous expression in adult and fetal tissues with higher expression in testis and peripheral blood leukocytes.

    Background: The Chromodomain-Helicase DNA-binding 1 is a protein that, in humans, is encoded by the CHD1 gene. The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template.

    分子量

    270 kDa

    基因ID

    1105

    UniProt

    O14646

    途径

    Chromatin Binding
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