HDAC9 抗体 (AA 7-469)
Quick Overview for HDAC9 抗体 (AA 7-469) (ABIN7602333)
抗原
See all HDAC9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 7-469
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原理
- Anti-HDAC9 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-HDAC9 Antibody Picoband® (ABIN7602333). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HDAC9 recombinant protein (Position: S7-Q469).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 4 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Mejat, A., Ramond, F., Bassel-Duby, R., Khochbin, S., Olson, E. N., Schaeffer, L. Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression. Nature Neurosci. 8: 313-321, 2005. 2. Sparrow, D. B., Miska, E. A., Langley, E., Reynaud-Deonauth, S., Kotecha, S., Towers, N., Spohr, G., Kouzarides, T., Mohun, T. J. MEF-2 function is modified by a novel co-repressor, MITR. EMBO J. 18: 5085-5098, 1999. 3. Zhou, X., Marks, P. A., Rifkind, R. A., Richon, V. M. Cloning and characterization of a histone deacetylase, HDAC9. Proc. Nat. Acad. Sci. 98: 10572-10577, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HDAC9 (Histone Deacetylase 9 (HDAC9))
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别名
- HDAC9
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背景
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Synonyms: Probetacellulin, Betacellulin, BTC, BTC
Tissue Specificity: Highly expressed in testis.
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
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分子量
- 150 kDa
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基因ID
- 9734
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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