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HDAC9 抗体 (C-Term)

HDAC9 适用: 人, 小鼠, 豚鼠, 绵羊 WB, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775576
发货至: 中国
  • 抗原 See all HDAC9 抗体
    HDAC9 (Histone Deacetylase 9 (HDAC9))
    抗原表位
    • 12
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 78
    • 27
    • 17
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 豚鼠, 绵羊
    宿主
    • 69
    • 9
    克隆类型
    • 62
    • 16
    多克隆
    标记
    • 43
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This HDAC9 antibody is un-conjugated
    应用范围
    • 51
    • 35
    • 34
    • 22
    • 21
    • 9
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
    序列
    QVGAVKVKEE PVDSDEDAQI QEMESGEQAA FMQQVIGKDL APGFVIKVII
    预测反应
    Guinea Pig: 100%, Human: 100%, Mouse: 100%, Sheep: 100%
    产品特性
    This is a rabbit polyclonal antibody against HDAC9. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human HDAC9
    Top Product
    Discover our top product HDAC9 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 590 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Spallotta, Tardivo, Nanni, Rosati, Straino, Mai, Vecellio, Valente, Capogrossi, Farsetti, Martone, Bozzoni, Pontecorvi, Gaetano, Colussi: "Detrimental effect of class-selective histone deacetylase inhibitors during tissue regeneration following hindlimb ischemia." in: The Journal of biological chemistry, Vol. 288, Issue 32, pp. 22915-29, (2013) (PubMed).

    Milde, Oehme, Korshunov, Kopp-Schneider, Remke, Northcott, Deubzer, Lodrini, Taylor, von Deimling, Pfister, Witt: "HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 12, pp. 3240-52, (2010) (PubMed).

    Hang, Yang, Han, Cheng, Shang, Ashley, Zhou, Chang: "Chromatin regulation by Brg1 underlies heart muscle development and disease." in: Nature, Vol. 466, Issue 7302, pp. 62-7, (2010) (PubMed).

  • 抗原
    HDAC9 (Histone Deacetylase 9 (HDAC9))
    别名
    HDAC9 (HDAC9 产品)
    别名
    HD7 antibody, HD7b antibody, HD9 antibody, HDAC antibody, HDAC7 antibody, HDAC7B antibody, HDAC9B antibody, HDAC9FL antibody, HDRP antibody, MITR antibody, AV022454 antibody, D030072B18Rik antibody, HD7B antibody, Hdac7b antibody, Mitr antibody, mKIAA0744 antibody, hdac9 antibody, zgc:73392 antibody, TWIST antibody, HDAC9 antibody, DKFZp459E171 antibody, HDA09 antibody, HISTONE DEACETYLASE antibody, histone deacetylase 9 antibody, RGD1310748 antibody, RGD1563092 antibody, hdac9-A antibody, histone deacetylase 9 antibody, histone deacetylase 9b antibody, histone deacetylase 9 S homeolog antibody, HDAC9 antibody, Hdac9 antibody, hdac9b antibody, HDA9 antibody, hdac9.S antibody
    背景
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC9 has sequence homology to members of the histone deacetylase family. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. HDAC9 may play a role in hematopoiesis.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
    Alias Symbols: DKFZp779K1053, HD7, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, KIAA0744, MITR, HD9, HD7b
    Protein Interaction Partner: NOP2, MKI67, EIF6, RCC1, ADAR, TOP1, TMPO, FIP1L1, CCAR2, TPX2, RBM14, ZC3H11A, HDAC9, NUP93, SMC3, H1FX, TPR, HINT1, CTBP1, BCL6, Zfp521, TRIM29, TP53, MAML1, SMARCA4, PARP1, CEBPB, H3F3A, RL2, CAMK1, YWHAE, HDAC1, SFN, MEF2B, ANKRA2, RFXANK, PKD1, SYK,
    Protein Size: 590
    分子量
    65 kDa
    基因ID
    9734
    NCBI登录号
    NM_014707, NP_055522
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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