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Occludin 抗体 (AA 7-367)

This anti-Occludin antibody is a 兔 多克隆 antibody detecting Occludin in WB 和 ELISA. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7602327
发货至: 中国

Quick Overview for Occludin 抗体 (AA 7-367) (ABIN7602327)

抗原

See all Occludin (OCLN) 抗体
Occludin (OCLN)

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Occludin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 7-367

    原理

    Anti-Occludin/Ocln Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Occludin/Ocln Antibody Picoband® (ABIN7602327). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Occludin/Ocln recombinant protein (Position: E7-Y367).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Ando-Akatsuka, Y., Saitou, M., Hirase, T., Kishi, M., Sakakibara, A., Itoh, M., Yonemura, S., Furuse, M., Tsukita, S. Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J. Cell Biol. 133: 43-47, 1996. 2. Argaw, A. T., Gurfein, B. T., Zhang, Y., Zameer, A., John, G. R. VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown. Proc. Nat. Acad. Sci. 106: 1977-1982, 2009. 3. Barrios-Rodiles, M., Brown, K. R., Ozdamar, B., Bose, R., Liu, Z., Donovan, R. S., Shinjo, F., Liu, Y., Dembowy, J., Taylor, I. W., Luga, V., Przulj, N., Robinson, M., Suzuki, H., Hayashizaki, Y., Jurisica, I., Wrana, J. L. High-throughput mapping of a dynamic signaling network in mammalian cells. Science 307: 1621-1625, 2005.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    Occludin (OCLN)

    别名

    Ocln

    背景

    Synonyms: Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2, CDKN1C, KIP2

    Tissue Specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver.

    Background: Occludin is an enzyme (EC 1.6) that oxidizes NADH. Predicted to enable protein domain specific binding activity. Involved in negative regulation of gene expression and tight junction organization. Located in several cellular components, including apical plasma membrane, apicolateral plasma membrane, and bicellular tight junction. Is expressed in several structures, including alimentary system, brain, genitourinary system, respiratory system, and sensory organ. Human ortholog(s) of this gene implicated in Crohn's disease and pseudo-TORCH syndrome 1. Orthologous to human OCLN (occludin).

    分子量

    59 kDa

    基因ID

    18260

    UniProt

    Q61146

    途径

    Cell-Cell Junction Organization, Hepatitis C
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