RGS6 抗体 (AA 7-357)
Quick Overview for RGS6 抗体 (AA 7-357) (ABIN7602326)
抗原
See all RGS6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 7-357
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原理
- Anti-RGS6 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-RGS6 Antibody Picoband® (ABIN7602326). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RGS6 recombinant protein (Position: D7-E357).
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亚型
- IgG
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anti-Regulator of G-Protein Signaling 6 (RGS6) (AA 177-262) antibody
RGS6 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 6 (RGS6) (AA 1-472) antibodyRGS6 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 6 (RGS6) (AA 1-472) antibodyRGS6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 6 (RGS6) (C-Term) antibodyRGS6 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 6 (RGS6) (AA 398-447) antibodyRGS6 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 斑马鱼, Bat, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 6 (RGS6) (C-Term) antibodyRGS6 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 斑马鱼, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 6 (RGS6) (AA 182-198) antibodyRGS6 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 6 (RGS6) (N-Term) antibodyRGS6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 6 (RGS6) (N-Term) antibodyRGS6 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 6 (RGS6) (N-Term) antibodyRGS6 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Berman, D. M., Wang, Y., Liu, Z., Dong, Q., Burke, L.-A., Liotta, L. A., Fisher, R., Wu, X. A functional polymorphism in RGS6 modulates the risk of bladder cancer. Cancer Res. 64: 6820-6826, 2004. 2. Chatterjee, T. K., Liu, Z., Fisher, R. A. Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants. J. Biol. Chem. 278: 30261-30271, 2003. 3. Posner, B. A., Gilman, A. G., Harris, B. A. Regulators of G protein signaling 6 and 7: purification of complexes with G-beta-5 and assessment of their effects on G protein-mediated signaling pathways. J. Biol. Chem. 274: 31087-31093, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RGS6 (Regulator of G-Protein Signaling 6 (RGS6))
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别名
- RGS6
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背景
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Synonyms: Protein phosphatase 1 regulatory subunit 14A,17 kDa PKC-potentiated inhibitory protein of PP1,Protein kinase C-potentiated inhibitor protein of 17 kDa,CPI-17,PPP1R14A,CPI17, PPP1INL,
Tissue Specificity: Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. .
Background: Regulator of G-protein signaling 6 is a protein that in humans is encoded by the RGS6 gene. This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.
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分子量
- 54 kDa
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基因ID
- 9628
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UniProt
- P49758
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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