PRELP 抗体 (AA 69-353)
Quick Overview for PRELP 抗体 (AA 69-353) (ABIN7602298)
抗原
See all PRELP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 69-353
-
原理
- Anti-PRELP Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-PRELP Antibody Picoband® (ABIN7602298). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human PRELP recombinant protein (Position: I69-R353).
-
亚型
- IgG
-
-
anti-Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) (AA 1-382) antibody
PRELP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) (AA 257-286), (C-Term) antibodyPRELP 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18591 unconjugated
anti-Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) antibodyPRELP 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) (AA 281-365) antibodyPRELP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) (AA 119-148) antibodyPRELP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB18590 unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bengtsson, E., Neame, P. J., Heinegard, D., Sommarin, Y. The primary structure of a basic leucine-rich repeat protein, PRELP, found in connective tissues. J. Biol. Chem. 270: 25639-25644, 1995. 2. Grover, J., Chen, X.-N., Korenberg, J. R., Recklies, A. D., Roughley, P. J. The gene organization, chromosome location, and expression of a 55- kDa matrix protein (PRELP) of human articular cartilage. Genomics 38: 109-117, 1996. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))
-
别名
- PRELP
-
背景
-
Synonyms: Cadherin-4, Retinal cadherin, R-CAD, R-cadherin, CDH4
Tissue Specificity: Expressed mainly in brain but also found in other tissues.
Background: Prolargin is a protein that in humans is encoded by the PRELP gene. The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.
-
分子量
- 65 kDa
-
基因ID
- 5549
-
UniProt
- P51888
-
途径
- Glycosaminoglycan Metabolic Process
抗原
-
