Desmoplakin 抗体 (AA 69-2195)
Quick Overview for Desmoplakin 抗体 (AA 69-2195) (ABIN7602296)
抗原
See all Desmoplakin (DSP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 69-2195
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原理
- Anti-Desmoplakin/DSP Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Desmoplakin/DSP Antibody (ABIN7602296). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Desmoplakin/DSP recombinant protein (Position: N69-H2195).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Desmoplakin (DSP)
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别名
- DSP
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背景
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Synonyms: Desmoplakin, DP, 250/210 kDa paraneoplastic pemphigus antigen, DSP
Tissue Specificity: Isoform DPI is apparently an obligate constituent of all desmosomes. Isoform DPII resides predominantly in tissues and cells of stratified origin.
Background: Desmoplakin is a protein in humans that is encoded by the DSP gene. This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.
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分子量
- 250 kDa
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基因ID
- 1832
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UniProt
- P15924
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途径
- Cell-Cell Junction Organization
抗原
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