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ATG16L1 抗体 (AA 66-359)

This anti-ATG16L1 antibody is a 兔 多克隆 antibody detecting ATG16L1 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人.
产品编号 ABIN7602244
发货至: 中国

Quick Overview for ATG16L1 抗体 (AA 66-359) (ABIN7602244)

抗原

See all ATG16L1 抗体
ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ATG16L1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 66-359

    原理

    Anti-ATG16L1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-ATG16L1 Antibody Picoband® (ABIN7602244). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ATG16L1 recombinant protein (Position: R66-K359).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Adolph, T. E., Tomczak, M. F., Niederreiter, L., Ko, H.-J., Bock, J., Martinez-Naves, E., Glickman, J. N., Tschurtschenthaler, M., Hartwig, J., Hosomi, S., Flak, M. B., Cusick, J. L., and 14 others. Paneth cells as a site of origin for intestinal inflammation. Nature 503: 272-276, 2013. 2. Bel, S., Pendse, M., Wang, Y., Li, Y., Ruhn, K. A., Hassell, B., Leal, T., Winter, S. E., Xavier, R. J., Hooper, L. V. Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine. Science 357: 1047-1052, 2017. 3. Boada-Romero, E., Serramito-Gomez, I., Sacristan, M. P., Boone, D. L., Xavier, R. J., Pimentel-Muinos, F. X. The T300A Crohn's disease risk polymorphism impairs function of the WD40 domain of ATG16L1. Nature Commun. 7: 11821, 2016. Note: Electronic Article.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

    别名

    ATG16L1

    背景

    Synonyms: Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, Afp

    Tissue Specificity: Plasma.

    Background: Autophagy related 16 like 1 is a protein that in humans is encoded by the ATG16L1 gene. The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

    分子量

    68 kDa

    基因ID

    55054

    UniProt

    Q676U5

    途径

    Autophagy
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