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CTNND1 抗体 (AA 64-930)

This anti-CTNND1 antibody is a 兔 多克隆 antibody detecting CTNND1 in WB, ELISA, IHC, IF, FACS 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602221
发货至: 中国

Quick Overview for CTNND1 抗体 (AA 64-930) (ABIN7602221)

抗原

See all CTNND1 抗体
CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CTNND1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
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    AA 64-930

    原理

    Anti-delta 1 Catenin/CAS/CTNND1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-delta 1 Catenin/CAS/CTNND1 Antibody Picoband® (ABIN7602221). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human delta 1 Catenin/CAS/CTNND1 recombinant protein (Position: H64-K930).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bonne, S., van Hengel, J., van Roy, F. Chromosomal mapping of human armadillo genes belonging to the p120(ctn)/plakophilin subfamily. Genomics 51: 452-454, 1998. 2. Dillon, D. A., D'Aquila, T., Reynolds, A. B., Fearon, E. R., Rimm, D. L. The expression of p120ctn protein in breast cancer is independent of alpha- and beta-catenin and E-cadherin. Am. J. Path. 152: 75-82, 1998. 3. Ghoumid, J., Stichelbout, M., Jourdain, A.-S., Frenois, F., Lejeune-Dumoulin, S., Alex-Cordier, M.-P., Lebrun, M., Guerreschi, P., Duquennoy-Martinot, V., Vinchon, M., Ferri, J., Jung, M., Vicaire, S., Vanlerberghe, C., Escande, F., Petit, F., Manouvrier-Hanu, S. Blepharocheilodontic syndrome is a CDH1 pathway-related disorder due to mutations in CDH1 and CTNND1. Genet. Med. 19: 1013-1021, 2017.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

    别名

    CTNND1

    背景

    Synonyms: Acid-sensing ion channel 1, ASIC1,Amiloride-sensitive cation channel 2, neuronal, Brain sodium channel 2, BNaC2, ASIC1, ACCN2, BNAC2

    Tissue Specificity: Expressed in most or all neurons.

    Background: p120, and called catenin delta-1 is a protein that in humans is encoded by the CTNND1 gene. This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene.

    分子量

    100-110 kDa

    基因ID

    1500

    UniProt

    O60716

    途径

    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
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