电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TULP3 抗体 (AA 62-362)

This anti-TULP3 antibody is a 兔 多克隆 antibody detecting TULP3 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7602191
发货至: 中国

Quick Overview for TULP3 抗体 (AA 62-362) (ABIN7602191)

抗原

See all TULP3 抗体
TULP3 (Tubby Like Protein 3 (TULP3))

适用

  • 27
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1

宿主

  • 21
  • 6

克隆类型

  • 23
  • 4
多克隆

标记

  • 18
  • 3
  • 2
  • 2
  • 1
  • 1
This TULP3 antibody is un-conjugated

应用范围

  • 22
  • 14
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 62-362

    原理

    Anti-TULP3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-TULP3 Antibody Picoband® (ABIN7602191). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TULP3 recombinant protein (Position: P62-H362).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Devane, J., Ott, E., Olinger, E. G., Epting, D., Decker, E., Friedrich, A., Bachmann, N., Renschler, G., Eisenberger, T., Briem-Richter, A., Grabhorn, E. F., Powell, L., and 24 others. Progressive liver, kidney, and heart degeneration in children and adults affected by TULP3 mutations. Am. J. Hum. Genet. 109: 928-943, 2022. 2. Ikeda, A., Ikeda, S., Gridley, T., Nishina, P. M., Naggert, J. K. Neural tube defects and neuroepithelial cell death in Tulp3 knockout mice. Hum. Molec. Genet. 10: 1325-1334, 2001. 3. Nishina, P. M., North, M. A., Ikeda, A., Yan, Y., Naggert, J. K. Molecular characterization of a novel tubby gene family member, TULP3, in mouse and humans. Genomics 54: 215-220, 1998.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    TULP3 (Tubby Like Protein 3 (TULP3))

    别名

    TULP3

    背景

    Synonyms: B-cell differentiation antigen CD72, Lyb-2, CD72, CD72

    Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

    Background: This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene.

    分子量

    60 kDa

    基因ID

    7289

    UniProt

    O75386

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
You are here:
Chat with us!