TULP3 抗体 (AA 62-362)
Quick Overview for TULP3 抗体 (AA 62-362) (ABIN7602191)
抗原
See all TULP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 62-362
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原理
 - Anti-TULP3 Antibody Picoband®
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交叉反应 (详细)
 - No cross-reactivity with other proteins.
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产品特性
 - Anti-TULP3 Antibody Picoband® (ABIN7602191). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
 - Immunogen affinity purified.
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免疫原
 - E.coli-derived human TULP3 recombinant protein (Position: P62-H362).
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亚型
 - IgG
 
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应用备注
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                        Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Devane, J., Ott, E., Olinger, E. G., Epting, D., Decker, E., Friedrich, A., Bachmann, N., Renschler, G., Eisenberger, T., Briem-Richter, A., Grabhorn, E. F., Powell, L., and 24 others. Progressive liver, kidney, and heart degeneration in children and adults affected by TULP3 mutations. Am. J. Hum. Genet. 109: 928-943, 2022. 2. Ikeda, A., Ikeda, S., Gridley, T., Nishina, P. M., Naggert, J. K. Neural tube defects and neuroepithelial cell death in Tulp3 knockout mice. Hum. Molec. Genet. 10: 1325-1334, 2001. 3. Nishina, P. M., North, M. A., Ikeda, A., Yan, Y., Naggert, J. K. Molecular characterization of a novel tubby gene family member, TULP3, in mouse and humans. Genomics 54: 215-220, 1998. - 
                                            
限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
 - 500 μg/mL
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缓冲液
 - Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
 - 4 °C,-20 °C
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储存方法
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                        At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. 
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- TULP3 (Tubby Like Protein 3 (TULP3))
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别名
 - TULP3
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背景
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Synonyms: B-cell differentiation antigen CD72, Lyb-2, CD72, CD72
Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.
Background: This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene.
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分子量
 - 60 kDa
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基因ID
 - 7289
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UniProt
 - O75386
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途径
 - Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
 
抗原
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