KISS1R 抗体 (AA 60-373)
Quick Overview for KISS1R 抗体 (AA 60-373) (ABIN7602153)
抗原
See all KISS1R 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 60-373
-
原理
- Anti-GPR54/KISS1R Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-GPR54/KISS1R Antibody Picoband® (ABIN7602153). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human GPR54/KISS1R recombinant protein (Position: N60-A373).
-
亚型
- IgG
-
-
anti-KISS1 Receptor (KISS1R) (Extracellular Domain) antibody
KISS1R 适用: 人, 小鼠, 大鼠, Cow, Pig, Bat, 犬, Hamster, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (C-Term) antibodyKISS1R 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (AA 121-200) antibodyKISS1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (C-Term) antibodyKISS1R 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (AA 292-305), (Extracellular) antibodyKISS1R 适用: 人 WB, IHC, IF, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (N-Term) antibodyKISS1R 适用: 人 IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (Cytoplasmic Domain) antibodyKISS1R 适用: 人, Cow, Pig, 山羊 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (AA 309-372) antibodyKISS1R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (AA 235-263) antibodyKISS1R 适用: 人 WB 宿主: 兔 Polyclonal RB40407 unconjugated
anti-KISS1 Receptor (KISS1R) (2nd Extracellular Domain) antibodyKISS1R 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Mikkelsen JD, Bentsen AH, Ansel L, Simonneaux V, Juul A (Jan 2009). "Comparison of the effects of peripherally administered kisspeptins". Regulatory Peptides. 152 (1-3): 95-100. 2. Neal-Perry G, Lebesgue D, Lederman M, Shu J, Zeevalk GD, Etgen AM (Aug 2009). "The excitatory peptide kisspeptin restores the luteinizing hormone surge and modulates amino acid neurotransmission in the medial preoptic area of middle-aged rats". Endocrinology. 150 (8): 3699-708. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- KISS1R (KISS1 Receptor (KISS1R))
-
别名
- KISS1R
-
背景
-
Synonyms: KiSS-1 receptor, KiSS-1R, G-protein coupled receptor 54, G-protein coupled receptor OT7T175, hOT7T175, Hypogonadotropin-1, Kisspeptins receptor, Metastin receptor, KISS1R, AXOR12, GPR54
Tissue Specificity: Most highly expressed in the pancreas, placenta and spinal cord, with lower-level of expression in peripheral blood leukocytes, kidney, lung, fetal liver, stomach, small intestine, testes, spleen, thymus, adrenal glands and lymph nodes. In the adult brain, expressed in the superior frontal gyrus, putamen, caudate nucleus, cingulate gyrus, nucleus accumbens, hippocampus, pons and amygdala, as well as the hypothalamus and pituitary. Expression levels are higher in early (7-9 weeks) than term placentas. Expression levels were increased in both early placentas and molar pregnancies and were reduced in choriocarcinoma cells. Expressed at higher levels in first trimester trophoblasts than at term of gestation. Also found in the extravillous trophoblast suggesting endocrine/paracrine activation mechanism.
Background: The KiSS1-derived peptide receptor (also known as GPR54 or the Kisspeptin receptor) is a G protein-coupled receptor which binds the peptide hormone kisspeptin (metastin). Kisspeptin is involved in the regulation of endocrine function and the onset of puberty, with activation of the kisspeptin receptor triggering release of gonadotropin-releasing hormone (GnRH), and release of kisspeptin itself being inhibited by oestradiol but enhanced by GnRH. Reductions in kisspeptin levels with age may conversely be one of the reasons behind age-related declines in levels of other endocrine hormones such as luteinizing hormone.
-
分子量
- 80 kDa
-
基因ID
- 84634
-
UniProt
- Q969F8
抗原
-
