SSB 抗体 (AA 6-283)
Quick Overview for SSB 抗体 (AA 6-283) (ABIN7602125)
抗原
See all SSB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-283
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原理
- Anti-SSB Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-SSB Antibody Picoband® (ABIN7602125). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SSB recombinant protein (Position: D6-L283).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bini, P., Chu, J.-L., Okolo, C., Elkon, K. Analysis of autoantibodies to recombinant La (SS-B) peptides in systemic lupus erythematosus and primary Sjogren's syndrome. J. Clin. Invest. 85: 325-333, 1990. 2. Chambers, J. C., Kenan, D., Martin, B. J., Keene, J. D. Genomic structure and amino acid sequence domains of the human La autoantigen. J. Biol. Chem. 263: 18043-18051, 1988. 3. Grolz, D., Bachmann, M. The nuclear autoantigen La/SS-associated antigen B: one gene, three functional mRNAs. Biochem. J. 323: 151-158, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SSB (Sjogren Syndrome Antigen B (SSB))
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别名
- SSB
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背景
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Synonyms: Plasminogen, PLG
Tissue Specificity: Present in plasma and many other extracellular fluids. It is synthesized in the liver.
Background: Sjgren syndrome type B antigen (SS-B) also known as Lupus La protein is a protein that in humans is encoded by the SSB gene. The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.
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分子量
- 47 kDa
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基因ID
- 6741
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UniProt
- P05455
抗原
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