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SSB 抗体 (AA 6-283)

This anti-SSB antibody is a 兔 多克隆 antibody detecting SSB in ELISA, WB, IHC, IF, FACS 和 ICC. Suitable for 人.
产品编号 ABIN7602125
发货至: 中国

Quick Overview for SSB 抗体 (AA 6-283) (ABIN7602125)

抗原

See all SSB 抗体
SSB (Sjogren Syndrome Antigen B (SSB))

适用

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宿主

  • 78
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克隆类型

  • 85
  • 10
多克隆

标记

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This SSB antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • 抗原表位

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    • 10
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    AA 6-283

    原理

    Anti-SSB Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SSB Antibody Picoband® (ABIN7602125). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SSB recombinant protein (Position: D6-L283).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bini, P., Chu, J.-L., Okolo, C., Elkon, K. Analysis of autoantibodies to recombinant La (SS-B) peptides in systemic lupus erythematosus and primary Sjogren's syndrome. J. Clin. Invest. 85: 325-333, 1990. 2. Chambers, J. C., Kenan, D., Martin, B. J., Keene, J. D. Genomic structure and amino acid sequence domains of the human La autoantigen. J. Biol. Chem. 263: 18043-18051, 1988. 3. Grolz, D., Bachmann, M. The nuclear autoantigen La/SS-associated antigen B: one gene, three functional mRNAs. Biochem. J. 323: 151-158, 1997.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SSB (Sjogren Syndrome Antigen B (SSB))

    别名

    SSB

    背景

    Synonyms: Plasminogen, PLG

    Tissue Specificity: Present in plasma and many other extracellular fluids. It is synthesized in the liver.

    Background: Sjgren syndrome type B antigen (SS-B) also known as Lupus La protein is a protein that in humans is encoded by the SSB gene. The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.

    分子量

    47 kDa

    基因ID

    6741

    UniProt

    P05455
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