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TYK2 抗体 (AA 581-719)

This anti-TYK2 antibody is a 兔多克隆 antibody detecting TYK2 in WB, ELISA 和 FACS. Suitable for 人.

产品编号 ABIN7602085

发货至: 中国

Quick Overview for TYK2 抗体 (AA 581-719) (ABIN7602085)

抗原

See all TYK2 抗体

TYK2 (Tyrosine Kinase 2 (TYK2))

适用

人

宿主

兔

克隆类型

多克隆

标记

45
5
4
4
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1

This TYK2 antibody is un-conjugated

应用范围

69
34
21
13
13
13
12
11
8
5
2

Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Discover our top product TYK2 Primary Antibody

抗原表位
17

15

15

7

5

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 581-719

原理

Anti-TYK2 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-TYK2 Antibody Picoband® (ABIN7602085). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human TYK2 recombinant protein (Position: F581-A719).

亚型

IgG
anti-Tyrosine Kinase 2 (TYK2) (AA 276-375) antibody
TYK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6H1 unconjugated

anti-Tyrosine Kinase 2 (TYK2) (AA 276-375) antibody
TYK2 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 6G12 unconjugated

anti-Tyrosine Kinase 2 (TYK2) (AA 750-850) antibody
TYK2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Kinase 2 (TYK2) (pTyr1054), (pTyr1055) antibody
TYK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Kinase 2 (TYK2) (AA 286-372) antibody
TYK2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Kinase 2 (TYK2) (AA 1-1187) antibody
TYK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Kinase 2 (TYK2) (C-Term) antibody
TYK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Kinase 2 (TYK2) antibody
TYK2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Kinase 2 (TYK2) antibody
TYK2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8G8B3 unconjugated

anti-Tyrosine Kinase 2 (TYK2) (AA 1020-1069) antibody
TYK2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Boisson-Dupuis, S., Ramirez-Alejo, N., Li, Z., Patin, E., Rao, G., Kerner, G., Lim, C. K., Krementsov, D. N., Hernandez, N., Ma, C. S., Zhang, Q., Markle, J., and 55 others. Tuberculosis and impaired IL-23-dependent IFN-gamma immunity in humans homozygous for a common TYK2 missense variant. Sci. Immun. 3: eaau8714, 2018. 2. Firmbach-Kraft, I., Byers, M., Shows, T., Dalla-Favera, R., Krolewski, J. J. tyk2, prototype of a novel class of non-receptor tyrosine kinase genes. Oncogene 5: 1329-1336, 1990. 3. Karaghiosoff, M., Neubauer, H., Lassnig, C., Kovarik, P., Schindler, H., Pircher, H., McCoy, B., Bogdan, C., Decker, T., Brem, G., Pfeffer, K., Muller, M. Partial impairment of cytokine responses in Tyk2-deficient mice. Immunity 13: 549-560, 2000.

限制

仅限研究用
状态

Lyophilized

溶解方式

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原

TYK2 (Tyrosine Kinase 2 (TYK2))

别名

TYK2

背景

Synonyms: RNA polymerase II-associated factor 1 homolog, hPAF1, Pancreatic differentiation protein 2, PAF1, PD2
Tissue Specificity: Isoform 1 is expressed in neurons of the cerebellum and hippocampus. Isoform 2 is expressed in thymus, spleen and lung.
Background: Non-receptor tyrosine-protein kinase TYK2 is an enzyme that in humans is encoded by the TYK2 gene. This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35.

分子量

134 kDa

基因ID

7297

UniProt

P29597

途径

JAK/STAT Signaling, Hepatitis C

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