LDHD 抗体 (AA 56-498)
Quick Overview for LDHD 抗体 (AA 56-498) (ABIN7602046)
抗原
See all LDHD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 56-498
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原理
- Anti-LDHD Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-LDHD Antibody Picoband® (ABIN7602046). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LDHD recombinant protein (Position: R56-Q498).
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亚型
- IgG
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anti-Lactate Dehydrogenase D (LDHD) (AA 310-507) antibody
LDHD 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase D (LDHD) (AA 1-507) antibodyLDHD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase D (LDHD) (AA 62-265) antibodyLDHD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase D (LDHD) (AA 35-62), (N-Term) antibodyLDHD 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB27170 unconjugated
anti-Lactate Dehydrogenase D (LDHD) (AA 351-450) antibodyLDHD 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase D (LDHD) antibodyLDHD 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase D (LDHD) (AA 1-507) antibodyLDHD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Lactate Dehydrogenase D (LDHD) (AA 431-480) antibodyLDHD 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Lactate Dehydrogenase D (LDHD) (AA 158-507) antibodyLDHD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Drabkin, M., Yogev, Y., Zeller, L., Zarivach, R., Zalk, R., Halperin, D., Wormser, O., Gurevich, E., Landau, D., Kadir, R., Perez, Y., Birk, O. S. Hyperuricemia and gout caused by missense mutation in D-lactate dehydrogenase. J. Clin. Invest. 129: 5163-5168, 2019. 2. Flick, M. J., Konieczny, S. F. Identification of putative mammalian D-lactate dehydrogenase enzymes. Biochem. Biophys. Res. Commun. 295: 910-916, 2002. 3. Monroe, G. R., van Eerde, A. M., Tessadori, F., Duran, K. J., Savelberg, S. M. C., van Alfen, J. C., Terhal, P. A., van der Crabben, S. N., Lichtenbelt, K. D., Fuchs, S. A., Gerrits, J., van Roosmalen, M. J., and 16 others. Identification of human D lactate dehydrogenase deficiency. Nature Commun. 10: 1477, 2019. Note: Electronic Article. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- LDHD (Lactate Dehydrogenase D (LDHD))
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别名
- LDHD
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Two naturally occurring forms of lactate dehydrogenase with similar but unique substrate specificities have been isolated in lower organisms including invertebrates, fungi, and prokaryotes. These dehydrogenase enzymes are L-lactate dehydrogenase and D-lactate dehydrogenase (LDHD) that are specific to the L and D isomers of lactate, respectively (PMID: 12127981). In lactic acid bacteria, LDHD plays a key role in anaerobic energy metabolism (PMID: 497162). Despite the identification of D-lactate and other D-2-hydroxyacids in prokaryotes, and the obvious connections and similarities to vertebrate metabolic pathways, very few mammalian D-2-hydroxyacid dehydrogenases have been found. LDHD has 2 isoforms with the molecular weight of 52 and 54 kDa, and can be detected as 45-54 kDa.
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分子量
- 45-50 kDa
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基因ID
- 197257
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途径
- Ribonucleoside Biosynthetic Process
抗原
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