RTN4R 抗体 (AA 56-416)
Quick Overview for RTN4R 抗体 (AA 56-416) (ABIN7602041)
抗原
See all RTN4R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 56-416
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原理
- Anti-Nogo receptor/NgR1/RTN4R Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Nogo receptor/NgR1/RTN4R Antibody Picoband® (ABIN7602041). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Nogo receptor/NgR1/RTN4R recombinant protein (Position: P56-R416).
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亚型
- IgG
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anti-Reticulon 4 Receptor (RTN4R) (AA 151-350) antibody
RTN4R 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 Receptor (RTN4R) (AA 366-381), (Extracellular) antibodyRTN4R 适用: 人 WB, IHC, FACS, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 Receptor (RTN4R) (AA 244-473) antibodyRTN4R 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 Receptor (RTN4R) antibodyRTN4R 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 Receptor (RTN4R) (AA 1-473) antibodyRTN4R 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 Receptor (RTN4R) antibodyRTN4R 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Reticulon 4 Receptor (RTN4R) (AA 1-473) antibodyRTN4R 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Reticulon 4 Receptor (RTN4R) (Internal Region) antibodyVerified RTN4R 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Reticulon 4 Receptor (RTN4R) (AA 366-381), (Extracellular) antibody (FITC)RTN4R 适用: 人 FACS 宿主: 兔 Polyclonal FITC
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Barton, W. A., Liu, B. P., Tzvetkova, D., Jeffrey, P. D., Fournier, A. E., Sah, D., Cate, R., Strittmatter, S. M., Nikolov, D. B. Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins. EMBO J. 22: 3291-3302, 2003. 2. Domeniconi, M., Cao, Z., Spencer, T., Sivasankaran, R., Wang, K. C., Nikulina, E., Kimura, N., Cai, H., Deng, K., Gao, Y., He, Z., Filbin, M. T. Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth. Neuron 35: 283-290, 2002. 3. Fournier, A. E., GrandPre, T., Strittmatter, S. M. Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature 409: 341-346, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RTN4R (Reticulon 4 Receptor (RTN4R))
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别名
- RTN4R
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背景
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Synonyms: Solute carrier family 2, facilitated glucose transporter member 9, Glucose transporter type 9, GLUT-9, Urate transporter, SLC2A9, GLUT9
Tissue Specificity: Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Isoform 2 is only detected in the apical membranes of polarized renal tubular cells and placenta. Isoform 1 and isoform 2 are detected in kidney membrane (at protein level).
Background: Reticulon 4 receptor (RTN4R) also known as Nogo-66 Receptor (NgR) or Nogo receptor 1 is a protein which in humans is encoded by the RTN4R gene. This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
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分子量
- 70 kDa
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基因ID
- 65078
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途径
- Neurotrophin Signaling Pathway
抗原
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