DAP Kinase 1 抗体 (AA 545-1159)
Quick Overview for DAP Kinase 1 抗体 (AA 545-1159) (ABIN7602007)
抗原
See all DAP Kinase 1 (DAPK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 545-1159
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原理
- Anti-DAPK1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-DAPK1 Antibody Picoband® (ABIN7602007). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DAPK1 recombinant protein (Position: H545-Q1159).
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亚型
- IgG
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anti-Death-Associated Protein Kinase 1 (DAPK1) (AA 1360-1389), (C-Term) antibody
DAPK1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB3033 unconjugated
anti-Death-Associated Protein Kinase 1 (DAPK1) (AA 1331-1430) antibodyDAPK1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 1 (DAPK1) (AA 1211-1310) antibodyDAPK1 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-Death-Associated Protein Kinase 1 (DAPK1) (Internal Region) antibodyDAPK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 1 (DAPK1) antibodyDAPK1 适用: 人, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 1 (DAPK1) (N-Term) antibodyDAPK1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 1 (DAPK1) antibodyDAPK1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 1 (DAPK1) (Ser296) antibodyDAPK1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 1 (DAPK1) (AA 1141-1430) antibodyDAPK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 1 (DAPK1) antibodyDAPK1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Deiss, L. P., Feinstein, E., Berissi, H., Cohen, O., Kimchi, A. Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. Genes Dev. 9: 15-30, 1995. 2. Feinstein, E., Druck, T., Kastury, K., Berissi, H., Goodart, S. A., Overhauser, J., Kimchi, A., Huebner, K. Assignment of DAP1 and DAPK: genes that positively mediate programmed cell death triggered by IFN-gamma--to chromosome regions 5p12.2 and 9q34.1, respectively. Genomics 29: 305-307, 1995. 3. Guenebeaud, C., Goldschneider, D., Castets, M., Guix, C., Chazot, G., Delloye-Bourgeois, C., Eisenberg-Lerner, A., Shohat, G., Zhang, M., Laudet, V., Kimchi, A., Bernet, A., Mehlen, P. The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase. Molec. Cell 40: 863-876, 2010. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- DAP Kinase 1 (DAPK1) (Death-Associated Protein Kinase 1 (DAPK1))
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别名
- DAPK1
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背景
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Synonyms: Interleukin-11, IL-11, Il11,
Tissue Specificity: Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
Background: Death-associated protein kinase 1 is an enzyme that in humans is encoded by the DAPK1 gene. Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants.
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分子量
- 160 kDa
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基因ID
- 1612
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UniProt
- P53355
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途径
- MAPK Pathway, Interferon-gamma Pathway
抗原
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