Adhesion G Protein-Coupled Receptor G1 (ADGRG1) (AA 53-554) 抗体
Quick Overview for Adhesion G Protein-Coupled Receptor G1 (ADGRG1) (AA 53-554) 抗体 (ABIN7601979)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 53-554
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原理
- Anti-Adgrg1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Adgrg1 Antibody Picoband® (ABIN7601979). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Adgrg1 recombinant protein (Position: E53-S554).
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亚型
- IgG
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anti-Adhesion G Protein-Coupled Receptor G1 (ADGRG1) (AA 26-216) antibody
ADGRG1 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adhesion G Protein-Coupled Receptor G1 (ADGRG1) (AA 86-109), (Extracellular) antibodyADGRG1 适用: 大鼠 FACS, WB, LCI 宿主: 兔 Polyclonal unconjugated
anti-Adhesion G Protein-Coupled Receptor G1 (ADGRG1) (Internal Region) antibodyADGRG1 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adhesion G Protein-Coupled Receptor G1 (ADGRG1) (AA 86-109), (Extracellular) antibody (FITC)ADGRG1 适用: 大鼠 FACS 宿主: 兔 Polyclonal FITC
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Bae, B.-I., Tietjen, I., Atabay, K. D., Evrony, G. D., Johnson, M. B., Asare, E., Wang, P. P., Murayama, A. Y., Im, K., Lisgo, S. N., Overman, L., Sestan, N., Chang, B. S., Barkovich, A. J., Grant, P. E., Topcu, M., Politsky, J., Okano, H., Piao, X., Walsh, C. A. Evolutionarily dynamic alternative splicing of GPR56 regulates regional cerebral cortical patterning. Science 343: 764-768, 2014. 2. Chiang, N.-Y., Hsiao, C.-C., Huang, Y.-S., Chen, H.-Y., Hsieh, I.-J., Chang, G.-W., Lin, H.-H. Disease-associated GPR56 mutations cause bilateral frontoparietal polymicrogyria via multiple mechanisms. J. Biol. Chem. 286: 14215-14225, 2011. 3. Kim, J.-E., Han, J. M., Park, C. R., Shin, K.-J., Ahn, C., Seong, J. Y., Hwang, J.-I. Splicing variants of the orphan G-protein-coupled receptor GPR56 regulate the activity of transcription factors associated with tumorigenesis. J. Cancer Res. Clin. Oncol. 136: 47-53, 2010. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Adhesion G Protein-Coupled Receptor G1 (ADGRG1)
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别名
- Adgrg1
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背景
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Synonyms: Phosphopantothenate--cysteine ligase, Phosphopantothenoylcysteine synthetase, PPC synthetase, PPCS, COAB
Tissue Specificity: Expressed in heart, placenta, skeletal muscle kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon. Expressed in lung endothelial and smooth muscle cells (at protein level).
Background: Enables several functions, including collagen binding activity, extracellular matrix binding activity, and heparin binding activity. Involved in several processes, including negative regulation of neuron migration, positive regulation of Rho protein signal transduction, and seminiferous tubule development. Acts upstream of or within cerebral cortex regionalization, hematopoietic stem cell homeostasis, and positive regulation of neural precursor cell proliferation. Located in glial limiting end-foot. Is expressed in several structures, including alimentary system, ganglia, genitourinary system, respiratory system, and sensory organ. Human ortholog(s) of this gene implicated in bilateral frontoparietal polymicrogyria and bilateral perisylvian polymicrogyria. Orthologous to human ADGRG1 (adhesion G protein-coupled receptor G1).
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分子量
- 78 kDa
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基因ID
- 14766
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UniProt
- Q8K209
抗原
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