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CD6 抗体 (AA 52-395)

This anti-CD6 antibody is a 兔 多克隆 antibody detecting CD6 in IHC 和 ELISA. Suitable for 大鼠.
产品编号 ABIN7601956
发货至: 中国

Quick Overview for CD6 抗体 (AA 52-395) (ABIN7601956)

抗原

See all CD6 抗体
CD6

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This CD6 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 52-395

    原理

    Anti-Cd6 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Cd6 Antibody Picoband® (ABIN7601956). Tested in ELISA, IHC applications. This antibody reacts with Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived rat Cd6 recombinant protein (Position: S52-Q395).

    亚型

    IgG
  • 应用备注

    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Rat
    ELISA, 0.1-0.5 μg/mL, Rat
    1. Aruffo, A., Melnick, M. B., Linsley, P. S., Seed, B. The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins. J. Exp. Med. 174: 949-952, 1991. 2. Bowen, M. A., Whitney, G. S., Neubauer, M., Starling, G. C., Palmer, D., Zhang, J., Nowak, N. J., Shows, T. B., Aruffo, A. Structure and chromosomal location of the human CD6 gene. J. Immun. 158: 1149-1156, 1997. 3. De Jager, P. L., Jia, X., Wang, J., de Bakker, P. I. W., Ottoboni, L., Aggarwal, N. T., Picco, L., Raychaudhuri, S., Tran, D., Aubin, C., Briskin, R., Romano, S., and 22 others. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nature Genet. 41: 776-782, 2009.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    CD6

    别名

    Cd6

    背景

    Synonyms: Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB

    Tissue Specificity: Pancreas-specific (at protein level). Loss of expression is seen in ductal type pancreas cancers.

    Background: CD6 (Cluster of Differentiation 6) is a human protein encoded by the CD6 gene. This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    52 kDa

    基因ID

    25752

    UniProt

    Q812A4
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