SPDEF/PSE 抗体 (AA 52-335)
Quick Overview for SPDEF/PSE 抗体 (AA 52-335) (ABIN7601954)
抗原
See all SPDEF/PSE (SPDEF) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 52-335
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原理
- Anti-PSE/SPDEF Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PSE/SPDEF Antibody Picoband® (ABIN7601954). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PSE/SPDEF recombinant protein (Position: E52-I335).
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亚型
- IgG
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anti-Proximal Sequence Element 1 (SPDEF) (AA 145-247) antibody
SPDEF 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proximal Sequence Element 1 (SPDEF) (AA 1-335) antibodySPDEF 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Proximal Sequence Element 1 (SPDEF) (AA 92-200) antibodySPDEF 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A5 unconjugated
anti-Proximal Sequence Element 1 (SPDEF) (AA 1-335) antibodySPDEF 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proximal Sequence Element 1 (SPDEF) (AA 182-231) antibodySPDEF 适用: 人, Cow, 兔, 犬, 豚鼠, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Proximal Sequence Element 1 (SPDEF) (AA 31-80) antibodySPDEF 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, Pig, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Proximal Sequence Element 1 (SPDEF) (C-Term) antibodySPDEF 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 豚鼠, 猴, Hamster, Bat, 小鸡, Drosophila melanogaster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Proximal Sequence Element 1 (SPDEF) (AA 74-123) antibodySPDEF 适用: 人, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Proximal Sequence Element 1 (SPDEF) (C-Term) antibodySPDEF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Oettgen, P., Finger, E., Sun, Z., Akbarali, Y., Thamrongsak, U., Boltax, J., Grall, F., Dube, A., Weiss, A., Brown, L., Quinn, G., Kas, K., Endress, G., Kunsch, C., Libermann, T. A. PDEF, a novel prostate epithelium-specific Ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression. J. Biol. Chem. 275: 1216-1225, 2000. 2. Park, K.-S., Korfhagen, T. R., Bruno, M. D., Kitzmiller, J. A., Wan, H., Wert, S. E., Hershey, G. K. K., Chen, G., Whitsett, J. A. SPDEF regulates goblet cell hyperplasia in the airway epithelium. J. Clin. Invest. 117: 978-988, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))
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别名
- SPDEF
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背景
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Synonyms: Type I iodothyronine deiodinase, 5DI, DIOI, Type 1 DI, Type-I 5'-deiodinase, DIO1, ITDI1, TXDI1
Tissue Specificity: Widely expressed in adult (at protein level) and fetal tissues.
Background: SAM pointed domain-containing Ets transcription factor is a protein that in humans is encoded by the SPDEF gene. The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 44 kDa
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基因ID
- 25803
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UniProt
- O95238
抗原
-
