IL-10 抗体 (AA 52-170)
Quick Overview for IL-10 抗体 (AA 52-170) (ABIN7601947)
抗原
See all IL-10 (IL10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 52-170
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原理
 - Anti-IL10 Antibody
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交叉反应 (详细)
 - No cross-reactivity with other proteins.
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产品特性
 - Anti-IL10 Antibody Picoband® (ABIN7601947). Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.
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纯化方法
 - Immunogen affinity purified.
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免疫原
 - E.coli-derived rat IL10 recombinant protein (Position: K52-A170).
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亚型
 - IgG
 
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应用备注
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                        Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL,
1. Eskdale J, Kube D, Tesch H, Gallagher G (1997). "Mapping of the human IL10 gene and further characterization of the 5' flanking sequence". - 
                                            
限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
 - 500 μg/mL
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缓冲液
 - Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
 - 4 °C,-20 °C
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储存方法
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                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. 
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- IL-10 (IL10) (Interleukin 10 (IL10))
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别名
 - Il10
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背景
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Synonyms: Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF, IL10
Tissue Specificity: Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.
Background: Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al. (1992) showed that the mouse IL 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al. (1997) mapped the IL10 gene to the junction between 1q31 and 1q32.
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分子量
 - 19 kDa
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基因ID
 - 25325
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UniProt
 - P29456
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途径
 - Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
 
抗原
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