MCU 抗体 (AA 51-351)
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- 抗原 See all MCU 抗体
- MCU (Mitochondrial Calcium Uniporter (MCU))
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抗原表位
- AA 51-351
- 适用
- 人, 小鼠, 大鼠, 猴
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MCU antibody is un-conjugated
- 应用范围
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)
- 原理
- Anti-MCU Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-MCU Antibody Picoband® (ABIN7601931). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human MCU recombinant protein (Position: V51-D351).
- 亚型
- IgG
- Top Product
- Discover our top product MCU Primary Antibody
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anti-Mitochondrial Calcium Uniporter (MCU) (AA 1-351) antibody
MCU 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Calcium Uniporter (MCU) (AA 155-233) antibodyMCU 适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Calcium Uniporter (MCU) (Internal Region) antibodyMCU 适用: 人, 小鼠 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Calcium Uniporter (MCU) (AA 191-206), (Mitochondrial Matrix) antibodyMCU 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Baughman, J. M., Perocchi, F., Girgis, H. S., Plovanich, M., Belcher-Timme, C. A., Sancak, Y., Bao, X. R., Strittmatter, L., Goldberger, O., Bagorad, R. L., Koteliansky, V., Mootha, V. K. Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature 476: 341-345, 2011. 2. De Stefani, D., Raffaello, A., Teardo, E., Szabo, I., Rizzuto, R. A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 476: 336-340, 2011. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 8/31/2011. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- MCU (Mitochondrial Calcium Uniporter (MCU))
- 别名
- MCU (MCU 产品)
- 背景
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Synonyms: Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, hIRE1p, Ire1-alpha, IRE1a, Serine/threonine-protein kinase, Endoribonuclease, ERN1
Tissue Specificity: Ubiquitously expressed. High levels observed in pancreatic tissue.
Background: The mitochondrial calcium uniporter (MCU) is a transmembrane protein that allows the passage of calcium ions from a cell's cytosol into mitochondria. Its activity is regulated by MICU1 and MICU2, which together with the MCU make up the mitochondrial calcium uniporter complex. This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants.
- 分子量
- 34 kDa
- 基因ID
- 90550
- 途径
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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