CDT1 抗体 (AA 508-546)
Quick Overview for CDT1 抗体 (AA 508-546) (ABIN7601923)
抗原
See all CDT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 508-546
-
原理
- Anti-CDT1/DUP Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-CDT1/DUP Antibody Picoband® (ABIN7601923). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human CDT1/DUP recombinant protein (Position: D508-L546).
-
亚型
- IgG
-
-
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) antibody
CDT1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (C-Term) antibodyVerified CDT1 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (C-Term) antibodyCDT1 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 兔, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (AA 12-170) antibodyCDT1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (C-Term) antibodyCDT1 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (AA 400-449) antibodyCDT1 适用: 人, 小鼠, 大鼠, Pig, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Licensing and DNA Replication Factor 1 (CDT1) (C-Term) antibodyCDT1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bicknell, L. S., Bongers, E. M. H. F., Leitch, A., Brown, S., Schoots, J., Harley, M. E., Aftimos, S., Al-Aama, J. Y., Bober, M., Brown, P. A. J., van Bokhoven, H., Dean, J., and 15 others. Mutations in the pre-replication complex cause Meier-Gorlin syndrome. Nature Genet. 43: 356-359, 2011. 2. Bongers, E. M. H. F., Opitz, J. M., Fryer, A., Sarda, P., Hennekam, R. C. M., Hall, B. D., Superneau, D. W., Harbison, M., Poss, A., van Bokhoven, H., Hamel, B. C. J., Knoers, N. V. A. M. Meier-Gorlin syndrome: report of eight additional cases and review. Am. J. Med. Genet. 102: 115-124, 2001. 3. Feingold, M. Meier-Gorlin syndrome. (Letter) Am. J. Med. Genet. 109: 338 only, 2002. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))
-
别名
- CDT1
-
背景
-
Synonyms: Lumican, Keratan sulfate proteoglycan lumican, KSPG lumican, LUM, LDC, SLRR2D,
Tissue Specificity: Cornea and other tissues.
Background: CDT1 (Chromatin licensing and DNA replication factor 1) is a protein that in humans is encoded by the CDT1 gene. The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein.
-
分子量
- 60 kDa
-
基因ID
- 81620
-
UniProt
- Q9H211
-
途径
- MAPK Pathway, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
-
