VAV3 抗体 (AA 507-702)
Quick Overview for VAV3 抗体 (AA 507-702) (ABIN7601922)
抗原
See all VAV3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 507-702
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原理
- Anti-VAV3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-VAV3 Antibody Picoband® (ABIN7601922). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human VAV3 recombinant protein (Position: D507-E702).
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亚型
- IgG
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anti-Vav 3 Oncogene (VAV3) (AA 183-380) antibody
VAV3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (Internal Region) antibodyVerified VAV3 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 701-800) antibodyVAV3 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 560-680) antibodyVAV3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 398-583) antibodyVAV3 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 562-674) antibodyVAV3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) antibodyVAV3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (pTyr173) antibodyVAV3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (pTyr173) antibodyVAV3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 768-802), (C-Term) antibodyVAV3 适用: 人 WB 宿主: 兔 Polyclonal RB53259 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bustelo, X. R. Regulatory and signaling properties of the Vav family. Molec. Cell. Biol. 20: 1461-1477, 2000. 2. Faccio, R., Teitelbaum, S. L., Fujikawa, K., Chappel, J., Zallone, A., Tybulewicz, V. L., Ross, F. P., Swat, W. Vav3 regulates osteoclast function and bone mass. Nature Med. 11: 284-290, 2005. 3. Moores, S. L., Selfors, L. M., Fredericks, J., Breit, T., Fujikawa, K., Alt, F. W., Brugge, J. S., Swat, W. Vav family proteins couple to diverse cell surface receptors. Molec. Cell. Biol. 20: 6364-6373, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- VAV3 (Vav 3 Oncogene (VAV3))
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别名
- VAV3
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背景
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Synonyms: Rapamycin-insensitive companion of mTOR, AVO3 homolog, hAVO3, RICTOR, KIAA1999
Tissue Specificity: In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
Background: Guanine nucleotide exchange factor VAV3 is a protein that in humans is encoded by the VAV3 gene. This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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分子量
- 98 kDa
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基因ID
- 10451
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途径
- Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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