XRN2 抗体 (AA 5-748)
Quick Overview for XRN2 抗体 (AA 5-748) (ABIN7601894)
抗原
See all XRN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-748
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原理
- Anti-XRN2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-XRN2 Antibody Picoband® (ABIN7601894). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human XRN2 recombinant protein (Position: A5-N748).
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亚型
- IgG
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anti-5'-3' Exoribonuclease 2 (XRN2) (AA 398-547) antibody
XRN2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 9F7G11 unconjugated
anti-5'-3' Exoribonuclease 2 (XRN2) antibodyXRN2 适用: 人, 小鼠, 猴 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 2 (XRN2) (AA 81-130) antibodyXRN2 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 2 (XRN2) (N-Term) antibodyXRN2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 2 (XRN2) (N-Term) antibodyXRN2 适用: 人, 小鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 2 (XRN2) (AA 48-76) antibodyXRN2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chatterjee, S., Grosshans, H. Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 461: 546-549, 2009. 2. Shobuike, T., Sugano, S., Yamashita, T., Ikeda, H. Characterization of cDNA encoding mouse homolog of fission yeast dhp1+ gene: structural and functional conservation. Nucleic Acids Res. 23: 357-361, 1995. 3. West, S., Gromak, N., Proudfoot, N. J. Human 5-prime to 3-prime exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites. Nature 432: 522-525, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- XRN2 (5'-3' Exoribonuclease 2 (XRN2))
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别名
- XRN2
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背景
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Synonyms: Proliferation-associated protein 2G4,Cell cycle protein p38-2G4 homolog,hG4-1,ErbB3-binding protein 1,PA2G4,EBP1,
Tissue Specificity: Isoform 2 is undetectable whereas isoform 1 is strongly expressed in cancer cells (at protein level). Isoform 1 and isoform 2 are widely expressed, including heart, brain, lung, pancreas, skeletal muscle, kidney, placenta and liver. .
Background: 5'-3' Exoribonuclease 2 (XRN2) also known as Dhm1-like protein is an exoribonuclease enzyme that in humans is encoded by the XRN2 gene. This gene encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 109 kDa
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基因ID
- 22803
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UniProt
- Q9H0D6
抗原
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