XPA 抗体 (AA 5-273)
Quick Overview for XPA 抗体 (AA 5-273) (ABIN7601877)
抗原
See all XPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-273
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原理
- Anti-XPA Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-XPA Antibody Picoband® (ABIN7601877). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human XPA recombinant protein (Position: D5-M273).
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亚型
- IgG
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anti-Xeroderma Pigmentosum, Complementation Group A (XPA) (Center) antibody
XPA 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group A (XPA) (AA 1-273) antibodyXPA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E4 unconjugated
anti-Xeroderma Pigmentosum, Complementation Group A (XPA) (AA 1-273) antibodyXPA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group A (XPA) (AA 1-273) antibodyXPA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group A (XPA) (Internal Region) antibodyXPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group A (XPA) (AA 211-260) antibodyXPA 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group A (XPA) (AA 221-250), (C-Term) antibodyXPA 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB23644 unconjugated
anti-Xeroderma Pigmentosum, Complementation Group A (XPA) (AA 185-213), (C-Term) antibodyXPA 适用: 人 WB 宿主: 兔 Polyclonal RB33699 unconjugated
anti-Xeroderma Pigmentosum, Complementation Group A (XPA) (C-Term) antibodyXPA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group A (XPA) (C-Term) antibodyXPA 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Li L, Elledge SJ, Peterson CA, Bales ES, Legerski RJ (May 1994). "Specific association between the human DNA repair proteins XPA and ERCC1". Proceedings of the National Academy of Sciences of the United States of America. 91 (11): 5012-6. 2. Nagai A, Saijo M, Kuraoka I, Matsuda T, Kodo N, Nakatsu Y, Mimaki T, Mino M, Biggerstaff M, Wood RD (Jun 1995). "Enhancement of damage-specific DNA binding of XPA by interaction with the ERCC1 DNA repair protein". Biochemical and Biophysical Research Communications. 211 (3): 960-6. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
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别名
- XPA
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背景
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Synonyms: Hepatocyte growth factor-regulated tyrosine kinase substrate, Hrs, Protein pp110, HGS, HRS
Tissue Specificity: Ubiquitous expression in adult and fetal tissues with higher expression in testis and peripheral blood leukocytes.
Background: DNA repair protein complementing XP-A cells is a protein that in humans is encoded by the XPA gene. This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.
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分子量
- 39 kDa
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基因ID
- 7507
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UniProt
- P23025
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途径
- DNA Damage Repair
抗原
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