EXOSC8 抗体 (AA 49-216)
Quick Overview for EXOSC8 抗体 (AA 49-216) (ABIN7601850)
抗原
See all EXOSC8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 49-216
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原理
- Anti-EXOSC8 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-EXOSC8 Antibody Picoband® (ABIN7601850). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human EXOSC8 recombinant protein (Position: A49-H216).
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亚型
- IgG
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anti-Exosome Component 8 (EXOSC8) (AA 1-276) antibody
EXOSC8 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G5 unconjugated
anti-Exosome Component 8 (EXOSC8) (AA 177-276) antibodyEXOSC8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B3 unconjugated
anti-Exosome Component 8 (EXOSC8) (AA 243-276), (C-Term) antibodyEXOSC8 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17686 unconjugated
anti-Exosome Component 8 (EXOSC8) antibodyEXOSC8 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 8 (EXOSC8) (AA 2-276) antibodyEXOSC8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 8 (EXOSC8) (AA 1-276) antibodyEXOSC8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Boczonadi, V., Muller, J. S., Pyle, A., Munkley, J., Dor, T., Quartararo, J., Ferrero, I., Karcagi, V., Giunta, M., Polvikoski, T., Birchall, D., Princzinger, A., and 15 others. EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia. Nature Commun. 5: 4287, 2014. Note: Electronic Article. 2. Chen, C.-Y., Gherzi, R., Ong, S.-E., Chan, E. L., Raijmakers, R., Pruijn, G. J. M., Stoecklin, G., Moroni, C., Mann, M., Karin, M. AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. Cell 107: 451-464, 2001. 3. Gross, M. B. Personal Communication. Baltimore, Md. 6/25/2014. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- EXOSC8 (Exosome Component 8 (EXOSC8))
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别名
- EXOSC8
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背景
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Synonyms: Homer protein homolog 3,Homer-3,HOMER3,
Tissue Specificity: Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Background: Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
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分子量
- 35 kDa
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基因ID
- 11340
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UniProt
- Q96B26
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途径
- SARS-CoV-2 Protein Interactome
抗原
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