EXOSC8 抗体 (AA 49-216)
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- 抗原 See all EXOSC8 抗体
- EXOSC8 (Exosome Component 8 (EXOSC8))
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抗原表位
- AA 49-216
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EXOSC8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- Anti-EXOSC8 Antibody Picoband®
- 交叉反应 (详细)
- No cross-reactivity with other proteins.
- 产品特性
- Anti-EXOSC8 Antibody Picoband® (ABIN7601850). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human EXOSC8 recombinant protein (Position: A49-H216).
- 亚型
- IgG
- Top Product
- Discover our top product EXOSC8 Primary Antibody
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Boczonadi, V., Muller, J. S., Pyle, A., Munkley, J., Dor, T., Quartararo, J., Ferrero, I., Karcagi, V., Giunta, M., Polvikoski, T., Birchall, D., Princzinger, A., and 15 others. EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia. Nature Commun. 5: 4287, 2014. Note: Electronic Article. 2. Chen, C.-Y., Gherzi, R., Ong, S.-E., Chan, E. L., Raijmakers, R., Pruijn, G. J. M., Stoecklin, G., Moroni, C., Mann, M., Karin, M. AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. Cell 107: 451-464, 2001. 3. Gross, M. B. Personal Communication. Baltimore, Md. 6/25/2014. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- EXOSC8 (Exosome Component 8 (EXOSC8))
- 别名
- EXOSC8 (EXOSC8 产品)
- 背景
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Synonyms: Homer protein homolog 3,Homer-3,HOMER3,
Tissue Specificity: Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Background: Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
- 分子量
- 35 kDa
- 基因ID
- 11340
- UniProt
- Q96B26
- 途径
- SARS-CoV-2 Protein Interactome
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