EXOSC8 抗体
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- 抗原 See all EXOSC8 抗体
- EXOSC8 (Exosome Component 8 (EXOSC8))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EXOSC8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- exosome component 8
- 亚型
- IgG
- Top Product
- Discover our top product EXOSC8 Primary Antibody
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anti-Exosome Component 8 (EXOSC8) (AA 1-276) antibody
EXOSC8 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G5 unconjugated
anti-Exosome Component 8 (EXOSC8) (AA 177-276) antibodyEXOSC8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B3 unconjugated
anti-Exosome Component 8 (EXOSC8) (AA 243-276), (C-Term) antibodyEXOSC8 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17686 unconjugated
anti-Exosome Component 8 (EXOSC8) antibodyEXOSC8 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 8 (EXOSC8) (AA 2-276) antibodyEXOSC8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- EXOSC8 (Exosome Component 8 (EXOSC8))
- 别名
- EXOSC8 (EXOSC8 产品)
- 别名
- wu:fb79a10 antibody, zgc:110381 antibody, MGC52847 antibody, MGC132146 antibody, EXOSC8 antibody, MGC79733 antibody, CIP3 antibody, EAP2 antibody, OIP2 antibody, RP11-421P11.3 antibody, RRP43 antibody, Rrp43p antibody, bA421P11.3 antibody, p9 antibody, 2310032N20Rik antibody, mKIAA4013 antibody, exosome component 8 antibody, exosome component 8 S homeolog antibody, Exosc8 antibody, exosc8 antibody, exosc8.S antibody, EXOSC8 antibody
- 背景
- Synonyms:OIP2, RRP43 Background:Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts(PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination(CSR) and/or Ig variable region somatic hypermutation(SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements(AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits(Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC8 binds to ARE-containing RNAs.
- 分子量
- 30-35 kDa
- 基因ID
- 11340
- UniProt
- Q96B26
- 途径
- SARS-CoV-2 Protein Interactome
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