SCARB2 抗体 (AA 48-357)
Quick Overview for SCARB2 抗体 (AA 48-357) (ABIN7601833)
抗原
See all SCARB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 48-357
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原理
- Anti-Scavenging Receptor SRB2/SCARB2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Scavenging Receptor SRB2/SCARB2 Antibody Picoband® (ABIN7601833). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Scavenging Receptor SRB2/SCARB2 recombinant protein (Position: E48-H357).
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亚型
- IgG
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anti-Scavenger Receptor Class B, Member 2 (SCARB2) (AA 47-128) antibody
SCARB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 2 (SCARB2) (AA 181-280) antibodySCARB2 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 2 (SCARB2) (AA 339-437) antibodySCARB2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 2 (SCARB2) (AA 25-74) antibodySCARB2 适用: 人, Cow, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 2 (SCARB2) (Internal Region) antibodyVerified SCARB2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 2 (SCARB2) (AA 1-478) antibodySCARB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 2 (SCARB2) (AA 339-437) antibodySCARB2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1C8 unconjugated
anti-Scavenger Receptor Class B, Member 2 (SCARB2) (AA 200-380) antibodySCARB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 2 (SCARB2) (N-Term) antibodySCARB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 2 (SCARB2) (C-Term) antibodySCARB2 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Badhwar, A., Berkovic, S. F., Dowling, J. P., Gonzales, M., Narayanan, S., Brodtmann, A., Berzen, L., Caviness, J., Trenkwalder, C., Winkelmann, J., Rivest, J., Lambert, M., Hernandez-Cossio, O., Carpenter, S., Andermann, F., Andermann, E. Action myoclonus-renal failure syndrome: characterization of a unique cerebro-renal disorder. Brain 127: 2173-2182, 2004. 2. Balreira, A., Gaspar, P., Caiola, D., Chaves, J., Beirao, I., Lopes Lima, J., Azevedo, J. E., Sa Miranda, M. C. A nonsense mutation in the LIMP-2 gene associated with progressive myoclonic epilepsy and nephrotic syndrome. Hum. Molec. Genet. 17: 2238-2243, 2008. 3. Berkovic, S. F., Dibbens, L. M., Oshlack, A., Silver, J. D., Katerelos, M., Vears, D. F., Lullmann-Rauch, R., Blanz, J., Zhang, K. W., Stankovich, J., Kalnins, R. M., Dowling, J. P., and 14 others. Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosis. Am. J. Hum. Genet. 82: 673-684, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
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别名
- SCARB2
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背景
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Synonyms: Sentrin-specific protease 6, SUMO-1-specific protease 1, Sentrin/SUMO-specific protease SENP6, SENP6, KIAA0797, SSP1, SUSP1, FKSG6
Tissue Specificity: Expressed in many tissues, highest levels in skeletal muscle.
Background: Lysosomal integral membrane protein 2 (LIMP-2) is a protein that in humans is encoded by the SCARB2 gene. The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 80 kDa
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基因ID
- 950
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UniProt
- Q14108
抗原
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