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SCARB2 抗体 (AA 48-357)

This anti-SCARB2 antibody is a 兔 多克隆 antibody detecting SCARB2 in WB, ELISA, IHC, FACS 和 IF. Suitable for 人.
产品编号 ABIN7601833
发货至: 中国

Quick Overview for SCARB2 抗体 (AA 48-357) (ABIN7601833)

抗原

See all SCARB2 抗体
SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

适用

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宿主

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克隆类型

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多克隆

标记

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This SCARB2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
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    AA 48-357

    原理

    Anti-Scavenging Receptor SRB2/SCARB2 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Scavenging Receptor SRB2/SCARB2 Antibody (ABIN7601833). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Scavenging Receptor SRB2/SCARB2 recombinant protein (Position: E48-H357).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

    别名

    SCARB2

    背景

    Synonyms: Sentrin-specific protease 6, SUMO-1-specific protease 1, Sentrin/SUMO-specific protease SENP6, SENP6, KIAA0797, SSP1, SUSP1, FKSG6

    Tissue Specificity: Expressed in many tissues, highest levels in skeletal muscle.

    Background: Lysosomal integral membrane protein 2 (LIMP-2) is a protein that in humans is encoded by the SCARB2 gene. The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    80 kDa

    基因ID

    950

    UniProt

    Q14108
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