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SMO 抗体 (AA 476-764)

This anti-SMO antibody is a 兔多克隆 antibody detecting SMO in WB, ELISA 和 FACS. Suitable for 人, 小鼠和大鼠.

产品编号 ABIN7601825

发货至: 中国

Quick Overview for SMO 抗体 (AA 476-764) (ABIN7601825)

抗原

See all SMO 抗体

SMO (Smoothened Homolog (Drosophila) (SMO))

适用

59
25
22
1
1
1
1
1
1
1
1

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

30
4
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This SMO antibody is un-conjugated

应用范围

46
30
13
12
9
6
4
2
2
1

Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Discover our top product SMO Primary Antibody

抗原表位
15

8

8

6

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 476-764

原理

Anti-Smoothened/SMO Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Smoothened/SMO Antibody Picoband® (ABIN7601825). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Smoothened/SMO recombinant protein (Position: N476-Q764).

亚型

IgG
anti-Smoothened Homolog (Drosophila) (SMO) (AA 551-650) antibody
SMO 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (AA 554-787) antibody
SMO 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (AA 28-233) antibody
SMO 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) antibody
SMO 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3D10 unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (1st Extracellular Domain) antibody
SMO 适用: 人, 小鼠 IHC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (N-Term) antibody
SMO 适用: 人, 小鼠, 大鼠, 犬, Bat, Cow, Hamster, 马, 猴, Pig, 兔 WB, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (AA 68-117) antibody
SMO 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (AA 653-787) antibody
SMO 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D9 unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (N-Term) antibody
SMO 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (N-Term) antibody
SMO 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Byrne, E. F. X., Sircar, R., Miller, P. S., Hedger, G., Luchetti, G., Nachtergaele, S., Tully, M. D., Mydock-McGrane, L., Covey, D. F., Rambo, R. P., Sansom, M. S. P., Newstead, S., Rohatgi, R., Siebold, C. Structural basis of Smoothened regulation by its extracellular domains. Nature 535: 517-522, 2016. 2. Chen, W., Ren, X.-R., Nelson, C. D., Barak, L. S., Chen, J. K., Beachy, P. A., de Sauvage, F., Lefkowitz, R. J. Activity-dependent internalization of Smoothened mediated by beta-arrestin 2 and GRK2. Science 306: 2257-2260, 2004. 3. Chen, Y., Struhl, G. Dual roles for Patched in sequestering and transducing hedgehog. Cell 87: 553-563, 1996.

限制

仅限研究用
状态

Lyophilized

溶解方式

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原

SMO (Smoothened Homolog (Drosophila) (SMO))

别名

SMO

背景

Synonyms: Peroxisome proliferator-activated receptor gamma,PPAR-gamma,Nuclear receptor subfamily 1 group C member 3,PPARG,NR1C3,
Tissue Specificity: Highest expression in adipose tissue. Lower in skeletal muscle, spleen, heart and liver. Also detectable in placenta, lung and ovary. .
Background: Smoothened is a protein that in humans is encoded by the SMO gene. The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.

分子量

86 kDa

基因ID

6608

UniProt

Q99835

途径

Hedgehog Signaling

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