CIT 抗体 (AA 470-1505)
Quick Overview for CIT 抗体 (AA 470-1505) (ABIN7601819)
抗原
See all CIT 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 470-1505
-
原理
- Anti-CIT Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-CIT Antibody Picoband® (ABIN7601819). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human CIT recombinant protein (Position: Q470-H1505). Human CIT shares 95.2% and 94.7% amino acid (aa) sequence identity with mouse and rat CIT, respectively.
-
亚型
- IgG
-
-
anti-Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT) antibody
CIT 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT) (AA 1928-2027) antibodyCIT 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT) (AA 1000-1300) antibodyCIT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Basit, S., Al-Harbi, K. M., Alhijji, S. A. M., Albalawi, A. M., Alharby, E., Eldardear, A., Samman, M. I. CIT, a gene involved in neurogenic cytokinesis, is mutated in human primary microcephaly. Hum. Genet. 135: 1199-1207, 2016. 2. Di Cunto, F., Calautti, E., Hsiao, J., Ong, L., Topley, G., Turco, E., Dotto, G. P. Citron Rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein citron. J. Biol. Chem. 273: 29706-29711, 1998. 3. Di Cunto, F., Imarisio, S., Hirsch, E., Broccoli, V., Bulfone, A., Migheli, A., Atzori, C., Turco, E., Triolo, R., Dotto, G. P., Silengo, L., Altruda, F. Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis. Neuron 28: 115-127, 2000. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- CIT (Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))
-
别名
- CIT
-
背景
-
Synonyms: CIT, CRIK, KIAA0949, STK21, Citron Rho-interacting kinase, CRIK, EC 2.7.11.1, Serine/threonine-protein kinase 21
Background: This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants.
-
分子量
- 231 kDa
-
基因ID
- 11113
-
UniProt
- O14578
-
途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
-
