c-FOS 抗体 (AA 45-293)
Quick Overview for c-FOS 抗体 (AA 45-293) (ABIN7601764)
抗原
See all c-FOS (c-Fos) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-293
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原理
- Anti-c-Fos/FOS Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-c-Fos/FOS Antibody Picoband® (ABIN7601764). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human c-Fos/FOS recombinant protein (Position: N45-D293).
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亚型
- IgG
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anti-c-Fos (c-Fos) antibody
c-Fos 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-c-Fos (c-Fos) (AA 283-295) antibodyVerified c-Fos 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-c-Fos (c-Fos) antibodyc-Fos 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Monoclonal 14C10 unconjugated Recombinant Antibody
anti-c-Fos (c-Fos) antibodyc-Fos 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 小鼠 Monoclonal 4B4F11 unconjugated
anti-c-Fos (c-Fos) (N-Term) antibodyc-Fos 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-c-Fos (c-Fos) (AA 211-380) antibodyc-Fos 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-c-Fos (c-Fos) (AA 1-380) antibodyc-Fos 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-c-Fos (c-Fos) (pThr325) antibodyc-Fos 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-c-Fos (c-Fos) (N-Term) antibodyc-Fos 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-c-Fos (c-Fos) (pThr232) antibodyc-Fos 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Barker, P. E., Rabin, M., Watson, M., Breg, W. R., Ruddle, F. H., Verma, I. M. : Human c-fos oncogene mapped within chromosomal region 14q21-q31. Proc. Nat. Acad. Sci. 81: 5826-5830, 1984. 2. Saez, E., Rutberg, S. E., Mueller, E., Oppenheim, H., Smoluk, J., Yuspa, S. H., Spiegelman, B. M. : c-fos is required for malignant progression of skin tumors. Cell 82: 721-732, 1995. 3. Grigoriadis, A. E., Wang, Z.-Q., Wagner, E. F. : Fos and bone cell development: lessons from a nuclear oncogene. Trends Genet. 11: :436-441, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- c-FOS (c-Fos) (c-Fos)
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别名
- FOS
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背景
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Synonyms: Receptor tyrosine-protein kinase erbB-4, Proto-oncogene-like protein c-ErbB-4, Tyrosine kinase-type cell surface receptor HER4, p180erbB4, ERBB4 intracellular domain, 4ICD, E4ICD, s80HER4, ERBB4, HER4
Tissue Specificity: Expressed at highest levels in brain, heart, kidney, in addition to skeletal muscle, parathyroid, cerebellum, pituitary, spleen, testis and breast. Lower levels in thymus, lung, salivary gland, and pancreas. Isoform JM-A CYT-1 and isoform JM-B CYT-1 are expressed in cerebellum, but only the isoform JM-B is expressed in the heart.
Background: The human oncogene c-fos is cellular homolog of the transforming gene of Finkel-Biskis-Jinkins (FBJ) murine osteosarcoma virus which was mapped to a single human chromosome. c-Fos is encoded by the FOS gene. FOS was the first transcription factor identified that has a critical function in regulating the development of cells destined to form and maintain the skeleton. FOS is also a major component of the activator protein-1 (AP-1) transcription factor complex, which includes members of the JUN family. c-fos is a major nuclear target for signal transduction pathways involved in the regulation of cell growth, differentiation, and transformation. Using transgenic and knockout mice, Grigoriadis et al. (1995) established a unique role for the proto-oncogene and nuclear transcription factor, Fos, in regulating the differentiation and activity of specific bone cell populations, both during normal development and in bone disease.
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分子量
- 50 kDa
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基因ID
- 2353
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UniProt
- P01100
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途径
- S100 Proteins
抗原
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