TNNT3 抗体 (AA 45-251)
Quick Overview for TNNT3 抗体 (AA 45-251) (ABIN7601762)
抗原
See all TNNT3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-251
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原理
- Anti-TNNT3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TNNT3 Antibody Picoband® (ABIN7601762). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TNNT3 recombinant protein (Position: A45-K251).
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亚型
- IgG
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anti-Fast Skeletal Troponin T (TNNT3) (AA 161-258) antibody
TNNT3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F12 unconjugated
anti-Fast Skeletal Troponin T (TNNT3) antibodyTNNT3 适用: 人, 小鸡, Quail WB, ELISA, IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal T1-61 unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (AA 161-258) antibodyTNNT3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (C-Term) antibodyTNNT3 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (AA 161-258) antibodyTNNT3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (C-Term) antibodyVerified TNNT3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (C-Term) antibody (Biotin)Verified TNNT3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal Biotin
anti-Fast Skeletal Troponin T (TNNT3) (AA 1-250) antibodyTNNT3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (AA 31-80) antibodyTNNT3 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 小鸡, Cow, 马, 犬, 山羊, 斑马鱼, 猴, Pig, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (C-Term) antibodyTNNT3 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Gurnett, C. A., Alaee, F., Desruisseau, D., Boehm, S., Dobbs, M. B. Skeletal muscle contractile gene (TNNT3, MYH3, TPM2): mutations not found in vertical talus or clubfoot. Clin. Orthop. Rel. Res. 467: 1195-1200, 2009. 2. Koch, A., Juan, T. S.-C., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., McNiece, I. K., Fletcher, F. A. cDNA cloning and chromosomal mapping of mouse fast skeletal muscle troponin T. Mammalian Genome 8: 346-348, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TNNT3 (Fast Skeletal Troponin T (TNNT3))
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别名
- TNNT3
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背景
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Synonyms: Troponin T, fast skeletal muscle, TnTf, Beta-TnTF, Fast skeletal muscle troponin T, fTnT, TNNT3
Tissue Specificity: In fetal and adult fast skeletal muscles, with a higher level expression in fetal than in adult muscle.
Background: Fast skeletal muscle troponin T (fTnT) is a protein that in humans is encoded by the TNNT3 gene. It is mapped to 11p15.5. The binding of Ca (2+) to the trimeric troponin complex initiates the process of muscle contraction. Increased Ca (2+) concentrations produce a conformational change in the troponin complex that is transmitted to tropomyosin dimers situated along actin filaments. The altered conformation permits increased interaction between a myosin head and an actin filament which, ultimately, produces a muscle contraction. The troponin complex has protein subunits C, I, and T. Subunit C binds Ca (2+) and subunit I binds to actin and inhibits actin-myosin interaction. Subunit T binds the troponin complex to the tropomyosin complex and is also required for Ca (2+)-mediated activation of actomyosin ATPase activity. There are 3 different troponin T genes that encode tissue-specific isoforms of subunit T for fast skeletal-, slow skeletal-, and cardiac-muscle. This gene encodes fast skeletal troponin T protein, also known as troponin T type 3. Alternative splicing results in multiple transcript variants encoding additional distinct troponin T type 3 isoforms. A developmentally regulated switch between fetal/neonatal and adult troponin T type 3 isoforms occurs. Additional splice variants have been described but their biological validity has not been established. Mutations in this gene may cause distal arthrogryposis multiplex congenita type 2B (DA2B).
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分子量
- 37 kDa
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基因ID
- 7140
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UniProt
- P45378
抗原
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