PALB2 抗体 (AA 45-1186)
Quick Overview for PALB2 抗体 (AA 45-1186) (ABIN7601758)
抗原
See all PALB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-1186
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原理
- Anti-PALB2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PALB2 Antibody Picoband® (ABIN7601758). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PALB2 recombinant protein (Position: K45-S1186).
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亚型
- IgG
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anti-Partner and Localizer of BRCA2 (PALB2) (AA 1101-1186) antibody
PALB2 适用: 人, Pig WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Partner and Localizer of BRCA2 (PALB2) (AA 675-725) antibodyPALB2 适用: 人 WB, IHC, IP, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Partner and Localizer of BRCA2 (PALB2) (AA 677-726) antibodyPALB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Partner and Localizer of BRCA2 (PALB2) (AA 99-198) antibodyPALB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Partner and Localizer of BRCA2 (PALB2) (AA 546-574) antibodyPALB2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB19074 unconjugated
anti-Partner and Localizer of BRCA2 (PALB2) (C-Term) antibodyPALB2 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-Partner and Localizer of BRCA2 (PALB2) (AA 553-582), (Middle Region) antibodyPALB2 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Antoniou, A. C., Casadei, S., Heikkinen, T., Barrowdale, D., Pylkas, K., Roberts, J., Lee, A., Subramanian, D., De Leeneer, K., Fostira, F., Tomiak, E., Neuhausen, S. L., and 36 others. Breast-cancer risk in families with mutations in PALB2. New Eng. J. Med. 371: 497-506, 2014. 2. Catucci, I., Peterlongo, P., Ciceri, S., Colombo, M., Pasquini, G., Barile, M., Bonanni, B., Verderio, P., Pizzamiglio, S., Foglia, C., Falanga, A., Marchetti, M., and 12 others. PALB2 sequencing in Italian familial breast cancer cases reveals a high-risk mutation recurrent in the province of Bergamo. Genet. Med. 16: 688-694, 2014. 3. Erkko, H., Xia, B., Nikkila, J., Schleutker, J., Syrjakoski, K., Mannermaa, A., Kallioniemi, A., Pylkas, K., Karppinen, S.-M., Rapakko, K., Miron, A., Sheng, Q., and 15 others. A recurrent mutation in PALB2 in Finnish cancer families. Nature 446: 316-319, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PALB2 (Partner and Localizer of BRCA2 (PALB2))
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别名
- PALB2
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背景
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Synonyms: Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1, Serpine1, Pai1, Planh1
Tissue Specificity: Ubiquitous.
Background: Partner and localizer of BRCA2, also known as PALB2 or FANCN, is a protein which in humans is encoded by the PALB2 gene. This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2.
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分子量
- 130 kDa
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基因ID
- 79728
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途径
- DNA Damage Repair
抗原
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