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VPS41 抗体 (AA 44-843)

VPS41 适用: 人, 小鼠, 大鼠 ELISA, WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7601748
发货至: 中国
  • 抗原 See all VPS41 抗体
    VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))
    抗原表位
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-843
    适用
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 13
    • 1
    • 1
    克隆类型
    • 15
    多克隆
    标记
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VPS41 antibody is un-conjugated
    应用范围
    • 6
    • 5
    • 4
    • 1
    ELISA, Western Blotting (WB), Flow Cytometry (FACS)
    原理
    Anti-VPS41 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-VPS41 Antibody Picoband® (ABIN7601748). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human VPS41 recombinant protein (Position: Q44-R843).
    亚型
    IgG
    Top Product
    Discover our top product VPS41 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/mL/1x10^6 cells, Human
    ELISA, 0.1-0.5 μg/mL/mL, Human
    1. Asensio, C. S., Sirkis, D. W., Maas, J. W., Jr., Egami, K., To, T.-L., Brodsky, F. M., Shu, X., Cheng, Y., Edwards, R. H. Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway. Dev. Cell 27: 425-437, 2013. 2. Cabrera, M., Langemeyer, L., Mari, M., Rethmeier, R., Orban, I., Perz, A., Brocker, C., Griffith, J., Klose, D., Steinhoff, H.-J., Reggiori, F., Engelbrecht-Vandre, S., Ungermann, C. Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering. J. Cell Biol. 191: 845-859, 2010. [PubMed: 21079247, images, related citations] [Full Text] 3. Hartz, P. A. Personal Communication. Baltimore, Md. 10/2/2009.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))
    别名
    VPS41 (VPS41 产品)
    背景

    Synonyms: E3 SUMO-protein ligase PIAS2, Androgen receptor-interacting protein 3, ARIP3, DAB2-interacting protein, DIP, E3 SUMO-protein transferase PIAS2, Msx-interacting zinc finger protein, Miz1, PIAS-NY protein, Protein inhibitor of activated STAT x, Protein inhibitor of activated STAT2, PIAS2, PIASX

    Tissue Specificity: Mainly expressed in testis. Isoform 3 is expressed predominantly in adult testis, weakly in pancreas, embryonic testis and sperm, and at very low levels in other organs.

    Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known.

    分子量
    99 kDa
    基因ID
    27072
    UniProt
    P49754
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