FOXF1 抗体 (AA 44-379)
Quick Overview for FOXF1 抗体 (AA 44-379) (ABIN7601744)
抗原
See all FOXF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 44-379
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原理
- Anti-FOXF1 Picoband® Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-FOXF1 Picoband® Antibody (ABIN7601744). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FOXF1 recombinant protein (Position: R44-M379).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Sen, P., Thakur, N., Stockton, D. W., Langston, C., Bejjani, B. A. Expanding the phenotype of alveolar capillary dysplasia (ACD). J. Pediat. 145: 646-651, 2004. 2. Sen, P., Yang, Y., Navarro, C., Silva, I., Szafranski, P., Kolodziejska, K. E., Dharmadhikari, A. V., Mostafa, H., Kozakewich, H., Kearney, D., Cahill, J. B., Whitt, M., and 70 others. Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain. Hum. Mutat. 34: 801-811, 2013. 3. Stankiewicz, P., Sen, P., Bhatt, S. S., Storer, M., Xia, Z., Bejjani, B. A., Ou, Z., Wiszniewska, J., Driscoll, D. J., Maisenbacher, M. K., Bolivar, J., Bauer, M., and 32 others. Genomic and genic deletions of the FOX gene cluster on 16q24.1 and inactivating mutations of FOXF1 cause alveolar capillary dysplasia and other malformations. Am. J. Hum. Genet. 84: 780-791, 2009. Note: Erratum: Am. J. Hum. Genet. 85: 537 only, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- FOXF1 (Forkhead Box F1 (FOXF1))
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别名
- FOXF1
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背景
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Synonyms: Forkhead box protein F1, Forkhead-related activator 1, FREAC-1, Forkhead-related protein FKHL5, Forkhead-related transcription factor 1, FOXF1, FKHL5, FREAC1
Tissue Specificity: Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas.
Background: Forkhead box protein F1 is a protein that in humans is encoded by the FOXF1 gene. It is mapped to 16q24.1. This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in the regulation of pulmonary genes as well as embryonic development.
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分子量
- 38-40 kDa
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基因ID
- 2294
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UniProt
- Q12946
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途径
- Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process
抗原
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